FB2024_03 , released June 25, 2024
Allele: Dmel\pumnanos.PB
Open Close
General Information
Symbol
Dmel\pumnanos.PB
Species
D. melanogaster
Name
nanos promoter construct of Barker
FlyBase ID
FBal0032527
Feature type
allele
Associated gene
Dmel\pum
Associated Insertion(s)
Carried in Construct
P{nanos-pum.B}
Key Links
Transgenic product class
wild_type
(Barker et al., 1992)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Barker et al., 1992)
Mutagen
in vitro construct
(Barker et al., 1992)
Progenitor genotype
Carried in construct
P{nanos-pum.B}
Cytology
Description

Minigene construct with pum cDNA driven by nos promoter.

(Barker et al., 1992)
Allele components
Component
Use(s)
Regulatory region(s)
nanos
Encoded product / tool
pum
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      pumnanos.PB rescues pum01688

      (Parisi and Lin, 1999)

      pumnanos.PB rescues pumMsc/pumFC8

      (Wharton et al., 1998)

      pumnanos.PB rescues pumunspecified

      (Barker et al., 1992)
      Partially rescues

      pumnanos.PB partially rescues pum02003

      (Parisi and Lin, 1999)

      pumnanos.PB partially rescues pum680

      (Wharton et al., 1998)
      Comments

      Rescues the preoogenic and oogenic defects of both pum02003 and pum01688 mutants; in rescued females most ovarioles contain actively dividing germline stem cells that support normal oogenesis and the females can produce progeny. Does not rescue the semi-lethality of pum02003.

      (Parisi and Lin, 1999)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      pumnanos.PB
      pumnos.PB
      Name Synonyms
      nanos promoter construct of Barker
      (Barker et al., 1992)
      Secondary FlyBase IDs
        References (5)