FB2024_03 , released June 25, 2024
Allele: Dmel\dppP23
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General Information
Symbol
Dmel\dppP23
Species
D. melanogaster
Name
FlyBase ID
FBal0034419
Feature type
allele
Associated gene
Dmel\dpp
Associated Insertion(s)
Carried in Construct
P{dpp-P23}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Padgett et al., 1993)
Progenitor genotype
Carried in construct
P{dpp-P23}
Cytology
Description

Contained within an 8kb genomic fragment that includes the dpp Hin region.

(Padgett et al., 1993)
Allele components
Component
Use(s)
Regulatory region(s)
dpp
Encoded product / tool
dpp
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Extra copies of dpp cause a broadening of the Mad activation domain in the dorsal epidermis of embryos.

      (Eldar et al., 2002)

      Dorsal epidermis is entirely absent and the ventral denticle belts for circumferential rings over the entire cuticle.

      (Gelbart, 1997.12.4)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      dppP23 is an enhancer of lethal | embryonic stage | recessive | partially phenotype of peb308

      (Reed et al., 2001)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      dppP23 rescues Df(2L)DTD48/dppH61

      (Padgett et al., 1993)
      Partially rescues

      dppP23 partially rescues dppunspecified

      (Gelbart, 1997.12.4)
      Comments

      Two copies fully rescues the embryonic phenotype of dppH61/Df(2L)DTD48.

      (Padgett et al., 1993)
      Images (0)
      Mutant
      Wild-type
      Stocks (4)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Dpdpp
      (Biehs et al., 1996)
      dpp+t8
      dppP23
      Name Synonyms
      Secondary FlyBase IDs
        References (15)