FB2024_03 , released June 25, 2024
Allele: Dmel\hbbcd.3UTR
Open Close
General Information
Symbol
Dmel\hbbcd.3UTR
Species
D. melanogaster
Name
FlyBase ID
FBal0039399
Feature type
allele
Associated gene
Dmel\hb
Associated Insertion(s)
Carried in Construct
P{hb-bcd3'UTR}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Schulz and Tautz, 1994)
Progenitor genotype
Carried in construct
P{hb-bcd3'UTR}
Cytology
Description

The maternal hb promoter drives the expression of the full hb coding sequence and part of the bcd 3' end that includes the anterior localisation sequence but not the nos response element (NRE).

(Schulz and Tautz, 1995)

Construct: cDNA of the maternal 3.2kb transcript including 1kb of sequence upstream from the maternal P1 promoter as well as a part of the bcd 3' UTR directly behind the stop codon of the hb coding region. The nos NREs are not included.

(Schulz and Tautz, 1994)
Allele components
Component
Use(s)
Regulatory region(s)
hb
Encoded product / tool
hb
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      hbbcd.3UTR is an enhancer of phenotype of bcdunspecified

      (Schulz and Tautz, 1994)
      Suppressor of
      Statement
      Reference

      hbbcd.3UTR/bcdunspecified is a suppressor of phenotype of tslunspecified

      (Schulz and Tautz, 1994)

      tslunspecified/hbbcd.3UTR is a suppressor of phenotype of bcdunspecified

      (Schulz and Tautz, 1994)

      hbbcd.3UTR is a suppressor of abdomen | ectopic phenotype of nanosbcd.3UTR

      (Schulz and Tautz, 1994)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Mutant phenotype of bcd mutant embryos is enhanced, due to ectopic activation of gt by hbbcd.3UTR. Mutant phenotype of bcd, tsl double mutants is partially rescued by hbbcd.3UTR. Double abdomen phenotype of nosbcd.3UTR is suppressed by hbbcd.3UTR.

      (Schulz and Tautz, 1994)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      hbbcd.3UTR partially rescues hb12

      (Schulz and Tautz, 1994)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      hbbcd.3UTR
      Name Synonyms
      Secondary FlyBase IDs
        References (2)