FlyBase Allele Report: Dmel\Ubx[unspecified]

General Information

Symbol

Dmel\Ubx^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0049236

Feature type

allele

Associated gene

Dmel\Ubx

Associated Insertion(s)

Carried in Construct

Also Known As

unspecified

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible | dominant | homeotic

(Prasad et al., 2003)

Phenotype Manifest In

haltere

(Prasad et al., 2003)

mesothoracic leg posterior compartment | somatic clone

(Minana and Garcia-Bellido, 1982)

presumptive embryonic/larval central nervous system

(Jimenez and Campos-Ortega, 1981)

wing | ectopic

(Prasad et al., 2003)

Detailed Description

Statement

Reference

Heterozygotes show mild transformations of haltere to wing.

(Prasad et al., 2003)

Antp^unspecified Ubx^unspecified embryos show transformation of the mesothoracic, metathoracic and first abdominal segments towards the prothoracic segment, and have bilaterally symmetric regions of sclerotised cuticle in the mesothoracic and metathoracic segments.

(Struhl, 1983)

Dominant mutation. Ubx^unspecified/Df(3R)P115 tissue in the posterior compartment of the mesothoracic legs shows transformation to the posterior compartment of the prothoracic leg in gynandromorphs.

(Minana and Garcia-Bellido, 1982)

Homozygous larvae have four intracortical bands, one at each of the first four neuromeres in the central nervous system.

(Jimenez and Campos-Ortega, 1981)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Ubx^unspecified is a suppressor of visible | recessive | somatic clone phenotype of Asx^xen-72-3

(Bischoff et al., 2009)

Phenotype Manifest In

Enhanced by

Statement

Reference

Ubx^unspecified has phenotype, enhanceable by Chi^k04405

(Morcillo and Dorsett, 1996)

Ubx^unspecified has phenotype, enhanceable by z^ae(bx)

(Lewis, 1959)

Suppressed by

Statement

Reference

Ubx^unspecified has phenotype, suppressible by skd²

(Lindsley and Zimm, 1992)

Enhancer of

Statement

Reference

Ubx^unspecified is an enhancer of eye phenotype of Scer\GAL4^GMR.PF, nej^ΔBHQ.UAS

(Anderson et al., 2005)

Ubx^unspecified is an enhancer of eye phenotype of Scer\GAL4^GMR.PF, nej^ΔQ.UAS

(Anderson et al., 2005)

Ubx^unspecified is an enhancer of phenotype of Antp^Scx

(Hannah-Alava, 1964)

Suppressor of

Statement

Reference

Ubx^unspecified is a suppressor of wing blade | somatic clone phenotype of Asx^xen-72-3

(Bischoff et al., 2009)

Other

Statement

Reference

Abd-B^unspecified, Antp^unspecified, Scr^unspecified, Ubx^unspecified, abd-A^unspecified has embryo | dorsal closure stage phenotype

(Perrin et al., 2004)

Antp^unspecified, Scr^unspecified, Ubx^unspecified, abd-A^unspecified has embryo | dorsal closure stage phenotype

(Perrin et al., 2004)

Antp^unspecified, Ubx^unspecified has abdominal segment 1 phenotype

(Struhl, 1983)

Additional Comments

Genetic Interactions

Statement

Reference

The severity of wing phenotypes caused by homozygous Asx^xen-72-3 mutant clones is reduced in a heterozygous Ubx^unspecified mutant background. For example, no necrotic or dual-lobed wings are observed. In addition, the percentage of wing blisters or folded/bent wings is reduced and fewer flies have crumpled wings. In some cases, ripples are associated with visible clones containing small cells, whereas other ripples are not associated with the presence of smaller cells.

(Bischoff et al., 2009)

Scr^unspecified, Antp^unspecified, Ubx^unspecified, abd-A^unspecified, Abd-B^unspecified mutants are profoundly affected in their development with abnormal or twisted dorsal closure.

(Perrin et al., 2004)

Expression of vg^Scer\UAS.cKa under the control of Scer\GAL4^bi-md653 in a Ubx^unspecified/+ background results in enhanced transformation of the haltere to wing.

(Prasad et al., 2003)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

The sensitivity of the metanotal transformation of the Ubx^unspecified/Ubx^bx-34e genotype to chromosomal rearrangements has been studied in the presence and absence of z^a.

(Babu and Bhat, 1981)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Ubx^unspecified

unspecified

(Struhl, 1983, Minana and Garcia-Bellido, 1982, Babu and Bhat, 1981, Jimenez and Campos-Ortega, 1981)

Name Synonyms

Secondary FlyBase IDs

References (16)

Report Sections

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