FB2024_03 , released June 25, 2024
Allele: Dmel\soghs.PY
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General Information
Symbol
Dmel\soghs.PY
Species
D. melanogaster
Name
heat shock construct of Yu
FlyBase ID
FBal0056124
Feature type
allele
Associated gene
Dmel\sog
Associated Insertion(s)
Carried in Construct
P{HS-sog}
Key Links
Transgenic product class
cDNA
(Yu et al., 1996)
wild_type
(Yu et al., 1996)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Yu et al., 1996)
wild_type
(Yu et al., 1996)
Mutagen
in vitro construct
(Yu et al., 1996)
Progenitor genotype
Carried in construct
P{HS-sog}
Cytology
Description

XbaI fragment of a sog cDNA (17.12) containing the full protein coding sequences is expressed under the control of an Hsp70 promoter.

(Yu et al., 1996)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
sog
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Heat induction of sog expression during a broad period of oogenesis leads to ventralization of the embryonic cuticle. A high percentage of eggs from these females remain unfertilized. Overexpression during stage 10 leads to ventralization of egg shell structures.

      (Araujo and Bier, 2000)

      Expression of soghs.PY in embryos results in a small decrease in the number of amnioserosa cells.

      (Yu et al., 2000)

      Heat induced expression during third instar larvae causes over 90% mortality, the few escapers have wild type wings. Heat induced expression between 0 and 16 hours and between 28 and 40 hours after pupariation causes truncation of wing vein L4. Heat induced expression between 16 and 28 hours causes truncation of wing vein L4 and L5 and/or the posterior crossvein. Heat-induced expression after 40 hours has no effect.

      (Yu et al., 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      soghs.PY is a suppressor | partially of amnioserosa phenotype of tsgunspecified

      (Yu et al., 2000)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      tsgunspecified embryos lack amnioserosa cells. This phenotype is partially rescued by the expression of soghs.PY.

      (Yu et al., 2000)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      soghs.PY partially rescues sogunspecified

      (Yu et al., 2000)
      Comments

      Partially rescues the reduction in the number of amnioserosa cells seen in sogunspecified embryos.

      (Yu et al., 2000)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      EP1
      soghs.PY
      Name Synonyms
      heat shock construct of Yu
      (Yu et al., 1996)
      Secondary FlyBase IDs
        References (5)