FB2024_03 , released June 25, 2024
Allele: Dmel\hhUAS.cPb
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General Information
Symbol
Dmel\hhUAS.cPb
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct b of Pignoni
FlyBase ID
FBal0057273
Feature type
allele
Associated gene
Dmel\hh
Associated Insertion(s)
Carried in Construct
P{UAS-hh.P}
Also Known As
UAS-hh
Key Links
Transgenic product class
cDNA
(Pignoni and Zipursky, 1997)
wild_type
(Pignoni and Zipursky, 1997)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Pignoni and Zipursky, 1997)
wild_type
(Pignoni and Zipursky, 1997)
Mutagen
in vitro construct
(Pignoni and Zipursky, 1997)
Progenitor genotype
Carried in construct
P{UAS-hh.P}
Cytology
Description

UASt regulatory sequences drive expression of a hh cDNA.

(Pignoni and Zipursky, 1997)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
hh
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of hhScer\UAS.cPb under the control of Scer\GAL4T155 results in a mirror-symmetric double-posterior pattern (posterior tergite, posterior hairy zone and intersegmental membrane) in the abdominal tergites. The mirror-image patterning or posterior tergite and posterior hairy zone structures caused by expression of hhScer\UAS.cPb under the control of Scer\GAL4T155 is unaffected if the flies are also homozygous for hhts2 (and raised at the restrictive temperature). The transformation of anterior tergite to intersegmental membrane is partly suppressed in these flies.

      (Kopp and Duncan, 2002)

      Scer\GAL4E132-mediated expression in the eye disc leads to massive overgrowth and induction of eye development throughout most of the region anterior to the morphogenetic furrow (MF). No obvious directionality to ommatidial recruitment is seen most likely reflecting the initiation of multiple MFs.

      (Pignoni and Zipursky, 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      NOT Suppressor of
      Statement
      Reference

      hhUAS.cPb/Scer\GAL4Act5C.PP is a non-suppressor of phenotype of enApa

      (Kopp and Duncan, 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of hhScer\UAS.cPb in clones under the control of Scer\GAL4Act5C.PP has no effect on cell fate or polarity in the abdominal tergites in enApa/+ adults.

      (Kopp and Duncan, 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      hhScer\UAS.cPb
      hhUAS.cPb
      Name Synonyms
      Saccharomyces cerevisiae UAS construct b of Pignoni
      (Pignoni and Zipursky, 1997)
      Secondary FlyBase IDs
        References (3)