FB2024_03 , released June 25, 2024
Allele: Dmel\Nrt::wgUAS.Tag:HA
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General Information
Symbol
Dmel\Nrt::wgUAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0058485
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-Nrt-flu-Wg, UAS-Nrt-wg, UAS-HA-Nrt-wg
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UAS regulatory sequences influences expression of wg-Nrt gene fusion (N-terminus of wg coding region fused to the C-terminus of Nrt and tagged at the N-terminus with 3 copies of the flu epitope).

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression under the control of Scer\GAL4hs.PB causes a larval naked phenotype.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Clones of cells in the anterior compartment of the dorsal epidermis of the adult abdomen (in the tergite) that are expressing Nrt::wgScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4αTub84B.PL in a dsunspecified background do not change the cell polarity of cells surrounding the clone.

Expression of Nrt::wgScer\UAS.T:Ivir\HA1 driven by Scer\GAL4wg.PM to wgl-17 flies rescues the phenotypes caused by wgl-17 alone.

Expression of Nrt::wgScer\UAS.T:Ivir\HA1 driven by Scer\GAL4en-e16E in a wgl-17 background rescues an expanse of naked cuticle only 1-2 cells wide. Cuticle posterior to row 6 that would be naked in wild type are covered in additional denticles.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Nrt::wgScer\UAS.T:Ivir\HA1
Nrt::wgUAS.T:HA1
Nrt::wgUAS.Tag:HA
Name Synonyms
Secondary FlyBase IDs
    References (13)