FlyBase Allele Report: Dmel\usp[tOa]

General Information

Symbol

Dmel\usp^tOa

Species

D. melanogaster

Name

FlyBase ID

FBal0059900

Feature type

allele

Associated gene

Dmel\usp

Associated Insertion(s)

Carried in Construct

P{usp^tOa}

Key Links

Genomic Maps

JBrowse

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Zelhof et al., 1997, Oro et al., 1992)

Progenitor genotype

Carried in construct

P{usp^tOa}

Cytology

Description

Construct: 8kb EcoRI genomic fragment containing usp.

(Oro et al., 1992)

8kb EcoRI fragment containing usp transcription unit.

(Oro et al., 1990)

Allele components

Component

Use(s)

Encoded product / tool

usp

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

rescue_region

X:2,036,836..2,044,901 [-]

Linked to:

EcoRI-EcoRI restriction fragment

(Oro et al., 1990)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

wild-type

(Lee et al., 2000, Schubiger and Truman, 2000, Zelhof et al., 1997, Oro et al., 1990)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Suppressor of

Statement

Reference

usp^tOa is a non-suppressor of lethal | recessive phenotype of l(1)2Cc²

(Oro et al., 1990)

usp^tOa is a non-suppressor of lethal | recessive phenotype of l(1)2Ce¹

(Oro et al., 1990)

usp^tOa is a non-suppressor of lethal | recessive phenotype of l(1)2Ce²

(Oro et al., 1990)

usp^tOa is a non-suppressor of lethal | recessive phenotype of l(1)2Ce³

(Oro et al., 1990)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

usp^tOa rescues usp^Δ148

(Chavoshi et al., 2010)

usp^tOa rescues usp^Δ148

(Wahlstrom et al., 2006)

usp^tOa rescues usp⁵

(Lee et al., 2000)

usp^tOa rescues usp³

(Lee et al., 2000)

usp^tOa rescues usp²

(Schubiger and Truman, 2000)

usp^tOa rescues usp³

(Zelhof et al., 1997)

usp^tOa rescues usp⁴

(Zelhof et al., 1997)

usp^tOa rescues usp³

(Oro et al., 1990)

usp^tOa rescues usp²

(Oro et al., 1990)

usp^tOa rescues usp⁴

(Oro et al., 1990)

Comments

The lethality of usp^Δ148 is rescued by expression of usp^tOa.

(Wahlstrom et al., 2006)

Rescues the γ neuron phenotype seen in usp³ clones generated in adult brains. Rescues the lethality of usp⁵ animals to adulthood.

(Lee et al., 2000)

Rescues the precocious differentiation of neurons seen in homozygous usp² clones in the margin region of the wing disc.

(Schubiger and Truman, 2000)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

8kb genomic fragment is sufficient for usp function.

(Oro et al., 1990)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

usp^tOa

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

Open Close