Amino acid replacement: R?K. The amino acid replacement is at a phosphate contacting Arginine residue within the second zinc finger of the DNA binding domain.
gamma-lobe & neuron | somatic clone
Homozygous ddaC dendritic arborisation neuron MARCM clones do not show dendrite branching defects.
Homozygous mutant γ neurons (generated in the adult brain as somatic clones) possess bifurcated axons, mimicking the larval type of projections, instead of having all axons projecting toward the midline as in wild-type. In larvae these neurons acquire the wild-type pattern of dendrites and axons, however pruning of the larval dendrites and axons are not observed during early metamorphosis. By 18 hours after puparium formation (APF), larval-specific axonal branches and most dendrites have been pruned in wild-type γ neurons, but mutant neurons retain larval dendrites and axonal branches.
l(X)48 and l(X)101 were found independently in an EMS screen, subsequent analysis shows that the phenotype is identical and both contain the same sole nucleotide substitution within the usp gene.
