FlyBase Allele Report: Rnor\Dlg1[UAS.cTa]

General Information

Symbol

Rnor\Dlg1^UAS.cTa

Species

R. norvegicus

Name

Saccharomyces cerevisiae UAS construct a of Thomas

FlyBase ID

FBal0060585

Feature type

allele

Associated gene

Rnor\Dlg1

Associated Insertion(s)

Carried in Construct

P{UAS-Rat\SAP97.T}

Transgenic product class

cDNA

(Thomas et al., 1997)

wild_type

(Thomas et al., 1997)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Thomas et al., 1997)

wild_type

(Thomas et al., 1997)

Mutagen

in vitro construct

(Thomas et al., 1997)

Progenitor genotype

Carried in construct

P{UAS-Rat\SAP97.T}

Cytology

Description

A Rnor\Dlg1 cDNA (31f2), comprising 225bp 5' untranslated sequences, a complete open reading frame (2697bp) and approximately 1.3kb 3' untranslated sequences, is expressed under the control of UASt regulatory sequences.

(Thomas et al., 1997)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Rnor\Dlg1

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^da.G32/Rnor\Dlg1^UAS.cTa is a suppressor of neoplasia phenotype of dlg1⁷

(Thomas et al., 1997)

Scer\GAL4^elav.PLu/Rnor\Dlg1^UAS.cTa is a suppressor of neoplasia phenotype of dlg1⁷

(Thomas et al., 1997)

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^da.G32/Rnor\Dlg1^UAS.cTa is a suppressor of phenotype of dlg1²

(Thomas et al., 1997)

Scer\GAL4^da.G32/Rnor\Dlg1^UAS.cTa is a suppressor of phenotype of dlg1⁵

(Thomas et al., 1997)

Scer\GAL4^da.G32/Rnor\Dlg1^UAS.cTa is a suppressor of imaginal disc phenotype of dlg1⁷

(Thomas et al., 1997)

NOT Suppressor of

Statement

Reference

Scer\GAL4^da.G32/Rnor\Dlg1^UAS.cTa is a non-suppressor of bouton phenotype of dlg1⁷

(Thomas et al., 1997)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Partially rescues the imaginal disc and brain tumour phenotypes of hemizygous dlg1⁷ males when expressed using Scer\GAL4^da.G32, resulting in viable adults in some cases when the flies contain two copies of Rnor\SAP97^Scer\UAS.cTa. Hemizygous dlg1² or dlg1⁵ males are partially rescued by one copy of Rnor\SAP97^Scer\UAS.cTa expressed using Scer\GAL4^da.G32. The neuromuscular junction presynaptic phenotype but not the tumour phenotype of hemizygous dlg1⁷ males is rescued when Rnor\SAP97^Scer\UAS.cTa is expressed using Scer\GAL4^elav.PLu.

(Thomas et al., 1997)

Rescues the increased number of active zones seen in hemizygous dlg1⁷ type I boutons if targeted to both pre- and postsynaptic cells using Scer\GAL4^unspecified.

(Thomas et al., 1997)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

Rat\SAP97^UAS.cTa

Rnor\Dlg1^Scer\UAS.cTa

Rnor\Dlg1^UAS.cTa

Rnor\SAP97^Scer\UAS.cTa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Thomas

(Thomas et al., 1997)

Secondary FlyBase IDs

References (2)

Report Sections

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