FB2024_03 , released June 25, 2024
Allele: Dmel\esgEP633
Open Close
General Information
Symbol
Dmel\esgEP633
Species
D. melanogaster
Name
FlyBase ID
FBal0089287
Feature type
allele
Associated gene
Dmel\esg
Associated Insertion(s)
P{EP}esgEP633
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Rorth et al., 1998)
Progenitor genotype
Associated Insertion(s)
P{EP}esgEP633
Cytology
Description

P{EP} insertion 460bp upstream of the esg translation initiation codon. The P{EP} element is oriented such that expression from the element should result in overexpression of esg.

(Bidet et al., 2003)
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of esgEP633 under the control of Scer\GAL4ey.PH has no effect on eye size.

      (Singh et al., 2005)

      Expression of esgEP633 under the control of Scer\GAL4ey.PH results in eyes that are slightly reduced in size.

      (Tseng and Hariharan, 2002)

      No obvious phenotype.

      (Ashburner et al., 1999)

      Expression of esgEP633 under the control of Scer\GAL4dpp.blk1 causes a mild reduction in the size of the wing, in the region between wing veins 3 and 4.

      (Rorth et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      esgEP633, Scer\GAL4GMR.PF is an enhancer of visible phenotype of HUAS.cMa, Scer\GAL4GMR.PF

      (Müller et al., 2005)
      Suppressor of
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      esgEP633, Scer\GAL4GMR.PF is an enhancer of eye phenotype of HUAS.cMa, Scer\GAL4GMR.PF

      (Müller et al., 2005)
      Suppressor of
      Statement
      Reference

      esgEP633/Scer\GAL4ey.PH is a suppressor of eye | ventral phenotype of L2

      (Singh et al., 2005)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The bang sensitivity of bss1/+ flies (more than 50% of flies are bang sensitive) is substantially suppressed by the expression of esgEP633 under the control of Scer\GAL4elav.PLu. However, the 100% bang sensitivity of bss1/bss1 flies is not suppressed by the expression of esgEP633 under the control of Scer\GAL4elav.PLu. The seizure sensitivity of eas2 flies is partially suppressed by expression of esgEP633 under the control of Scer\GAL4elav.PLu; the mean seizure threshold is raised to 13.3 +/- 3.2 V (for a high frequency stimulus of 0.5msec pulses delivered at 200Hz for 300 msec).

      (Hekmat-Scafe et al., 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      EP(2)0633
      (Ashburner et al., 1999.10.12)
      esgEP633
      Name Synonyms
      Secondary FlyBase IDs
        References (10)