FB2024_03 , released June 25, 2024
Allele: Dmel\csw::Src64BC583S.hs.2sev
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General Information
Symbol
Dmel\csw::Src64BC583S.hs.2sev
Species
D. melanogaster
Name
FlyBase ID
FBal0090463
Feature type
allele
Associated gene
csw::Src64B
Associated Insertion(s)
Carried in Construct
P{SE-cswC583Ssrc90}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Allard et al., 1998)
Progenitor genotype
Carried in construct
P{SE-cswC583Ssrc90}
Cytology
Description

Construct: Amino acid replacement: C583S. sev enhancers and an Hsp70 promoter drive expression of the first 90 amino acids of Src64B (containing a myristylation site) fused to mutated csw.

(Allard et al., 1998)
Allele components
Component
Use(s)
Encoded product / tool
csw::Src64B
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing csw::Src64BC583S.hs.2sev in a wild-type background do not have rough eyes, although the R7 photoreceptor cell is missing in approximately 10% of ommatidia.

      (Allard et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      csw::Src64BC583S.hs.2sev is a suppressor of phenotype of csw6

      (Allard et al., 1998)

      csw::Src64BC583S.hs.2sev is a suppressor of phenotype of cswG547E.hs.2sev

      (Allard et al., 1998)
      NOT Suppressor of
      Statement
      Reference

      csw::Src64BC583S.hs.2sev is a non-suppressor of phenotype of csw13-87

      (Allard et al., 1998)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      csw::Src64BC583S.hs.2sev
      Name Synonyms
      Secondary FlyBase IDs
        References (2)