FB2024_03 , released June 25, 2024
Allele: Dmel\kniUAS.cLa
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General Information
Symbol
Dmel\kniUAS.cLa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Lunde
FlyBase ID
FBal0092911
Feature type
allele
Associated gene
Dmel\kni
Associated Insertion(s)
Carried in Construct
P{UAS-kni.L}
Key Links
Transgenic product class
wild_type
(Lunde et al., 1998)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Lunde et al., 1998)
Mutagen
in vitro construct
(Lunde et al., 1998)
Progenitor genotype
Carried in construct
P{UAS-kni.L}
Cytology
Description

The full length kni coding region is expressed under the control of UASt regulatory sequences.

(Lunde et al., 1998)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
kni
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing kniScer\UAS.cLa under the control of Scer\GAL4Bx-MS1096 have abnormal wings; the dorsal surface appears to be one large amorphous expanse of vein tissue with densely packed trichomes and darkly pigmented cuticle. Macrochaetae are frequently missing from the thorax and femurs of the metathoracic legs are often twisted.

      (Lunde et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      kniUAS.cLa/Scer\GAL4kni.L2 rescues kniri-1

      (Lunde et al., 2003)
      Partially rescues

      kniUAS.cLa/Scer\GAL4Bx-MS1096 partially rescues kniri-1

      (Lunde et al., 1998)
      Comments

      Expression of kniScer\UAS.cLa under the control of Scer\GAL4kni.L2 rescues the L2 wing vein phenotype of kniri-1 flies.

      (Lunde et al., 2003)

      The L2 wing vein truncation phenotype of kniri-1 is rescued with high penetrance by kniScer\UAS.cLa expressed under the control of Scer\GAL4Bx-MS1096, but the rescued vein is consistently displaced anteriorly relative to the normal position of the L2 vein.

      (Lunde et al., 1998)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      kniScer\UAS.cLa
      kniUAS.cLa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Lunde
      (Lunde et al., 1998)
      Secondary FlyBase IDs
        References (3)