FB2024_03 , released June 25, 2024
Allele: Dmel\scaΔ41-463.UAS
Open Close
General Information
Symbol
Dmel\scaΔ41-463.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0093792
Feature type
allele
Associated gene
Dmel\sca
Associated Insertion(s)
Carried in Construct
P{UAS-sca.Δ41-463}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Lee et al., 1998)
Progenitor genotype
Carried in construct
P{UAS-sca.Δ41-463}
Cytology
Description

UASt regulatory sequences drive expression of sca in which amino acids 41 to 463 have been deleted and replaced by the amino acids Gly and Thr.

(Lee et al., 1998)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
sca
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of scaΔ41-463.Scer\UAS under the control of Scer\GAL4dpp.blk1 has no effect on wing development. Expression of scaΔ41-463.Scer\UAS under the control of Scer\GAL4h-1J3 has no effect on wing vein development.

      (Lee et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      Scer\GAL4sca-73-1/scaΔ41-463.UAS fails to rescue sca73-1/scaBP2

      (Lee et al., 1998)
      Comments

      scaΔ41-463.Scer\UAS expressed under the control of Scer\GAL4sca-73-1 does not rescue the scaBP2/sca73-1 extra thoracic bristle phenotype, and causes the number of ectopic bristles to increase compared to the number seen in scaBP2/sca73-1 flies.

      (Lee et al., 1998)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      scaΔ41-463.Scer\UAS
      scaΔ41-463.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)