FB2024_03 , released June 25, 2024
Allele: Dmel\inscCen.UAS.lacZ
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General Information
Symbol
Dmel\inscCen.UAS.lacZ
Species
D. melanogaster
Name
FlyBase ID
FBal0096877
Feature type
allele
Associated gene
Dmel\insc
Associated Insertion(s)
Carried in Construct
P{UAS-insc.Cen.T:lacZ}
Key Links
Transgenic product class
inframe_deletion
(Knoblich et al., 1999)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Knoblich et al., 1999)
Mutagen
in vitro construct
(Knoblich et al., 1999, Knoblich et al., 1999)
Progenitor genotype
Carried in construct
P{UAS-insc.Cen.T:lacZ}
Cytology
Description

UAS regulatory sequences drive expression of amino acids 252 to 615 of insc tagged with lacZ.

(Knoblich et al., 1999)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
insc
Tagged with
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      embryonic epidermis & spindle, with Scer\GAL4h-1J3

      (Knoblich et al., 1999)
      Detailed Description
      Statement
      Reference

      inscCen.Scer\UAS.T:Ecol\lacZ expressed in epidermal cells under the control of Scer\GAL4h-1J3 causes reorientation of mitotic spindles in these cells.

      (Knoblich et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      inscCen.UAS.lacZ/Scer\GAL4hs.PB rescues Df(2R)P72

      (Knoblich et al., 1999)
      Comments

      The spindle orientation defect seen in Df(2R)P72 neuroblasts is rescued by inscCen.Scer\UAS.T:Ecol\lacZ expressed under the control of Scer\GAL4hs.PB.

      (Knoblich et al., 1999)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      inscCen.Scer\UAS.T:Ecol\lacZ
      inscCen.UAS.lacZ
      Name Synonyms
      Secondary FlyBase IDs
        References (5)