FB2024_03 , released June 25, 2024
Allele: Dmel\HUAS.cHa
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General Information
Symbol
Dmel\HUAS.cHa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Haenlin
FlyBase ID
FBal0097257
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-H
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

Expression of H coding region is governed by UAS regulatory sequences.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

When expression is driven by Scer\GAL4btl.PS, ectopic fusions occur between adjacent dorsal branches and terminal branching is repressed. The cells involved in the ectopic fusions become tightly attached by an intercellular junction. Terminal branches arising from the dorsal branches are stunted and those arising from primary branches are fewer than wild type and stunted. Sporadically (and more often when expression is driven by Scer\GAL4tracheal), dorsal branches and ganglionic branches extend ectopic terminal branches. The number of tracheal cells is not affected nor is primary branching. Cell markers indicate a transformation of presumptive terminal or antifusion cells into fusion cells.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhancer of
Additional Comments
Genetic Interactions
Statement
Reference

The addition of HScer\UAS.cHa to Su(H)Scer\UAS.cKa, Scer\GAL4dpp.blk1 flies greatly enhances the wing nick phenotype seen in Su(H)Scer\UAS.cKa, Scer\GAL4dpp.blk1 flies alone. The size of the wing is greatly reduced.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
HScer\UAS.cHa
HUAS.cHa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Haenlin
Secondary FlyBase IDs
    References (3)