FB2024_03 , released June 25, 2024
Allele: Dmel\Ptp69DUAS.Tag:MYC
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General Information
Symbol
Dmel\Ptp69DUAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0098314
Feature type
allele
Associated gene
Dmel\Ptp69D
Associated Insertion(s)
Carried in Construct
P{UAS-Ptp69D.myc}
Key Links
Transgenic product class
wild_type
(Garrity et al., 1999)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Garrity et al., 1999)
Mutagen
in vitro construct
(Garrity et al., 1999)
Progenitor genotype
Carried in construct
P{UAS-Ptp69D.myc}
Cytology
Description

UASt regulatory sequences drive expression of wild type Ptp69D. Also has a Tag:MYC at 3' end.

(Garrity et al., 1999)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Ptp69D
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4ppk.PU/Ptp69DUAS.Tag:MYC rescues Ptp69DCRISPR.14/Df(3L)8ex34

      (Poe et al., 2017)

      Ptp69DUAS.Tag:MYC/Scer\GAL4elav.PLu rescues Ptp69D1

      (Garrity et al., 1999)
      Comments

      The strong decrease in the total and terminal dendrite density as well as terminal dendrite number observed in class IV dendrite arborizing neurons in Ptp69DCRISPR.14/Df(3L)8ex34 third instar larvae is fully rescued by expression of Ptp69DScer\UAS.T:Hsap\MYC under the control of Scer\GAL4ppk.PU in the mutant background.

      (Poe et al., 2017)

      Fully rescues the R1-R6 targeting phenotype in Ptp69D1/Df(3L)8ex34 larvae when expressed under the control of Scer\GAL4elav.PLu.

      (Garrity et al., 1999)
      Images (0)
      Mutant
      Wild-type
      Stocks (3)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Carried in plasmid "pUAS-Ptp69D-myc" and transfected into S2 cells for assay for proteolytic cleavage of Ptp69D gene product.

      (Garrity et al., 1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ptp69DScer\UAS.T:Hsap\MYC
      Ptp69DUAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (6)