FB2024_03 , released June 25, 2024
Allele: Dmel\Pi3K92Eunspecified
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General Information
Symbol
Dmel\Pi3K92Eunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0098330
Feature type
allele
Associated gene
Dmel\Pi3K92E
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Egg chambers containing Pi3K92Eunspecified mutant germline clones arrest development between stage two and four. Centrosomes are correctly positioned at the posterior pole of the oocyte.

        (Jagut et al., 2013)

        Mosaic flies in which the head is mutant for Pi3K92Eunspecified (clones generated using the "eyFLP" system) have smaller eyes than controls.

        (Oldham et al., 2002)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        NOT suppressed by
        Statement
        Reference

        Pi3K92Eunspecified has lethal phenotype, non-suppressible by Pten2L100/Pten117

        (Oldham et al., 2002)

        Pi3K92Eunspecified has decreased body size | somatic clone phenotype, non-suppressible by Pten117/Pten117

        (Oldham et al., 2002)
        Enhancer of
        Statement
        Reference

        Pi3K92Eunspecified is an enhancer of decreased body size phenotype of chicounspecified

        (Bohni et al., 1999)
        Phenotype Manifest In
        Suppressor of
        Statement
        Reference

        Pi3K92Eunspecified/Pi3K92E[+] is a suppressor of phenotype of mir-278KO

        (Teleman and Cohen, 2006)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        The leanness of mir-278KO homozygotes is largely suppressed by Pi3K92Eunspecified/+.

        (Teleman and Cohen, 2006)

        Expression of a catalytically inactive form of Pi3K92E in homozygous chicounspecified wing discs leads to a further reduction in size by 48%.

        (Bohni et al., 1999)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Pi3K92Eunspecified
        Name Synonyms
        Secondary FlyBase IDs
          References (5)