FlyBase Allele Report: Dmel\Nipped-A[323]

General Information

Symbol

Dmel\Nipped-A³²³

Species

D. melanogaster

Name

FlyBase ID

FBal0098365

Feature type

allele

Associated gene

Dmel\Nipped-A

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

loss of function allele

Mutagen

gamma ray

Nature of the Allele

Allele class

loss of function allele

(Rollins et al., 1999)

Mutagen

gamma ray

(Rollins et al., 1999)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die before end of larval stage | recessive

(Rollins et al., 1999)

some die during larval stage | recessive

(Rollins et al., 1999)

Phenotype Manifest In

Detailed Description

Statement

Reference

Recessive lethality acts at the L2-L3 molt.

(Rollins et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Nipped-A³²³ is a non-enhancer of visible phenotype of Ubx^bx-34e, su(Hw)^e2

(Rollins et al., 1999)

NOT Suppressor of

Statement

Reference

Nipped-A³²³ is a non-suppressor of visible phenotype of Ubx^bx-34e, su(Hw)^e2

(Rollins et al., 1999)

Other

Statement

Reference

Nipped-A[+]/Nipped-A³²³, vg¹ has visible | dominant phenotype

(Rollins et al., 1999)

Nipped-A[+]/Nipped-A³²³, mam^g2.1 has visible | dominant phenotype

(Rollins et al., 1999)

Phenotype Manifest In

Enhancer of

Statement

Reference

Nipped-A[+]/Nipped-A³²³ is an enhancer of wing margin phenotype of mam^g2.1

(Gause et al., 2006)

Nipped-A[+]/Nipped-A³²³ is an enhancer of wing blade phenotype of N^nd-1

(Gause et al., 2006)

Nipped-A³²³ is an enhancer of phenotype of mam^g2.1

(Rollins et al., 1999)

Nipped-A[+]/Nipped-A³²³ is an enhancer of wing phenotype of ct^L32, su(Hw)^e2

(Rollins et al., 1999)

Nipped-A³²³ is an enhancer of phenotype of vg¹

(Rollins et al., 1999)

Nipped-A³²³ is an enhancer of wing phenotype of ct^53d

(Rollins et al., 1999)

NOT Enhancer of

Statement

Reference

Nipped-A³²³ is a non-enhancer of phenotype of wg^l-17

(Rollins et al., 1999)

Nipped-A³²³ is a non-enhancer of phenotype of ap^56f

(Rollins et al., 1999)

Nipped-A³²³ is a non-enhancer of phenotype of Chi^e5.5

(Rollins et al., 1999)

Suppressor of

Statement

Reference

Nipped-A[+]/Nipped-A³²³ is a suppressor of wing vein L4 phenotype of N^Ax-E2

(Gause et al., 2006)

Nipped-A³²³ is a suppressor of eye phenotype of N^spl-1

(Rollins et al., 1999)

Other

Statement

Reference

Nipped-A³²³, vg[+]/vg¹ has wing phenotype

(Rollins et al., 1999)

Nipped-A³²³, mam^g2.1/mam[+] has wing phenotype

(Rollins et al., 1999)

Nipped-A[+]/Nipped-A³²³, vg¹ has wing phenotype

(Rollins et al., 1999)

Nipped-A[+]/Nipped-A³²³, mam^g2.1 has wing phenotype

(Rollins et al., 1999)

Additional Comments

Genetic Interactions

Statement

Reference

Heterozygosity for Nipped-A³²³ further reduces the width of N^nd-1 wings.

Wing vein L4 is shortened in N^Ax-E2 mutants; heterozygosity for Nipped-A³²³ increases the length of L4.

Heterozygosity for Nipped-A³²³ increases the number of wing margin nicks seen in mam^g2.1 heterozygotes.

(Gause et al., 2006)

Dominantly enhances the cut wing phenotype of ct^L32, su(Hw)^e2. Enhancement of wing phenotype of vg¹ is slight. Partially suppresses the eye phenotype of N^spl-1.

(Rollins et al., 1999)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Complements

Nipped-A^C25

(Rollins et al., 1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Nipped-A³²³

(Gause et al., 2006)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

Open Close