FB2024_03 , released June 25, 2024
Allele: Dmel\HphS030304
Open Close
General Information
Symbol
Dmel\HphS030304
Species
D. melanogaster
Name
FlyBase ID
FBal0100117
Feature type
allele
Associated gene
Dmel\Hph
Associated Insertion(s)
P{lacW}HphS030304
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Deak et al., 1997)
P-element activity
(Szeged Stock Center, 1998-)
Progenitor genotype
Associated Insertion(s)
P{lacW}HphS030304
Cytology
Description

P{lacW} inserted 1111 bp upstream of putative transcription start site of Hph.

(Frei and Edgar, 2004)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      HphS030304/Hph02255 animals develop normally until pupariation, but very few escaper adults eclose. These escapers are smaller than their heterozygous siblings (18% lighter), but have normal body proportions.

      (Frei and Edgar, 2004)

      Lethal phase is from the pharate adult stage onwards.

      (Deak et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Hph[+]/HphS030304 is a suppressor | partially of ommatidium phenotype of Cdk4UAS.cMa, CycDUAS.cDa, Scer\GAL4GMR.PF

      (Frei and Edgar, 2004)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      HphS030304/+ partially suppresses the increase in size of ommatidia and interommatidial bristles seen in the eyes of Cdk4Scer\UAS.cMa; CycDScer\UAS.cDa; Scer\GAL4GMR.PF flies.

      (Frei and Edgar, 2004)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      HphS030304/Hph02255 is rescued by HphUAS.cFa/Scer\GAL4hs.PB

      (Frei and Edgar, 2004)
      Comments

      P{UAS-Hph.F}II.1; HphII.2; Scer\GAL4hs.PB rescues the lethality of Hph02255/HphS030304 even in the absence of heat shock. HphScer\UAS.cFa rescues the increase in ommatidial size in Cdk4Scer\UAS.cMa; CycDScer\UAS.cDa; Scer\GAL4GMR.PF suppressed by Hph02255/+.

      (Frei and Edgar, 2004)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      0303/04
      (Deak et al., 1997)
      HphS030304
      l(3)S030304
      (Frei and Edgar, 2004)
      l(3)S030304S030304
      Name Synonyms
      Secondary FlyBase IDs
        References (3)