FlyBase Allele Report: Dmel\H[UAS.cGb]

General Information

Symbol

Dmel\H^UAS.cGb

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Giebel

FlyBase ID

FBal0100424

Feature type

allele

Associated gene

Dmel\H

Associated Insertion(s)

Carried in Construct

P{UAS-H.Gb}

Key Links

Transgenic product class

wild_type

(Giebel, 1999)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Giebel, 1999)

Mutagen

in vitro construct

(Giebel, 1999)

Progenitor genotype

Carried in construct

P{UAS-H.Gb}

Cytology

Description

The H coding region is driven by UAS regulatory sequences.

(Giebel, 1999)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

embryonic/larval somatic muscle cell, with Scer\GAL4^da.G32

(Giebel, 1999)

embryonic/larval somatic muscle cell, with Scer\GAL4^how-24B

(Giebel, 1999)

muscle founder cell, with Scer\GAL4^da.G32

(Giebel, 1999)

muscle founder cell, with Scer\GAL4^how-24B

(Giebel, 1999)

peripheral nervous system, with Scer\GAL4^da.G32

(Giebel, 1999)

Detailed Description

Statement

Reference

Expression of H^Scer\UAS.cGb driven by Scer\GAL4^da.G32 or Scer\GAL4^how-24B leads to a slight increase in number of muscle founder cells. This correlates with an increase in the number of differentiated muscle fibres. H^Scer\UAS.cGb driven by Scer\GAL4^da.G32 also leads to a weakly hyperplasic nervous system.

(Giebel, 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

H^UAS.cGb, Scer\GAL4^da.G32 is a suppressor of muscle founder cell phenotype of N^int.SH.UAS, Scer\GAL4^da.G32

(Giebel, 1999)

H^UAS.cGb, Scer\GAL4^da.G32 is a suppressor of embryonic/larval somatic muscle cell phenotype of N^int.SH.UAS, Scer\GAL4^da.G32

(Giebel, 1999)

H^UAS.cGb, Scer\GAL4^da.G32 is a suppressor of visceral muscle fiber phenotype of N^int.SH.UAS, Scer\GAL4^da.G32

(Giebel, 1999)

H^UAS.cGb, Scer\GAL4^da.G32 is a suppressor of central nervous system phenotype of N^int.SH.UAS, Scer\GAL4^da.G32

(Giebel, 1999)

H^UAS.cGb, Scer\GAL4^da.G32 is a suppressor of peripheral nervous system phenotype of N^int.SH.UAS, Scer\GAL4^da.G32

(Giebel, 1999)

H^UAS.cGb, Scer\GAL4^how-24B is a suppressor of muscle founder cell phenotype of N^int.SH.UAS, Scer\GAL4^how-24B

(Giebel, 1999)

H^UAS.cGb, Scer\GAL4^how-24B is a suppressor of embryonic/larval somatic muscle cell phenotype of N^int.SH.UAS, Scer\GAL4^how-24B

(Giebel, 1999)

H^UAS.cGb, Scer\GAL4^how-24B is a suppressor of visceral muscle fiber phenotype of N^int.SH.UAS, Scer\GAL4^how-24B

(Giebel, 1999)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of H^Scer\UAS.cGb and N^{int.SH.Scer\UAS} driven by Scer\GAL4^da.G32 or Scer\GAL4^how-24B produces embryos with fewer muscle founder cells than wild-type, but more than seen in embryos with N^{int.SH.Scer\UAS} alone (driven by Scer\GAL4^da.G32 or Scer\GAL4^how-24B) alone. Also well differentiated muscles are found, in contrast to N^{int.SH.Scer\UAS} alone. Co-expression of H^Scer\UAS.cGb and N^{int.SH.Scer\UAS} driven by Scer\GAL4^da.G32 CNS and some PNS structures are seen to differentiate in contrast to N^{int.SH.Scer\UAS} alone (driven by Scer\GAL4^da.G32).

(Giebel, 1999)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

H^Scer\UAS.cGb

H^UAS.cGb

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Giebel

(Giebel, 1999)

Secondary FlyBase IDs

References (1)

Report Sections

Open Close