FB2024_03 , released June 25, 2024
Allele: Dmel\jarHsp83.PH
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General Information
Symbol
Dmel\jarHsp83.PH
Species
D. melanogaster
Name
Heat shock protein 83 promoter construct of Hicks
FlyBase ID
FBal0102663
Feature type
allele
Associated gene
Dmel\jar
Associated Insertion(s)
Carried in Construct
P{Hsp83-jar.H}
Key Links
Transgenic product class
cDNA
(Hicks et al., 1999)
wild_type
(Hicks et al., 1999)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Hicks et al., 1999)
wild_type
(Hicks et al., 1999)
Mutagen
in vitro construct
(Hicks et al., 1999)
Progenitor genotype
Carried in construct
P{Hsp83-jar.H}
Cytology
Description

An Hsp83 promoter drives expression of a full length cDNA encoding the EMC isoform of jar.

(Hicks et al., 1999)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp83
Encoded product / tool
jar
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of jarHsp83.PH results in actin cones that are initially similar in shape to wild-type but become wider after the onset of cystic bulge movement due to increased actin accumulation.

      (Noguchi et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      jarHsp83.PH rescues jarcrb87-5/jar322

      (Morrison and Miller, 2008)

      jarHsp83.PH rescues jarmmw14/Df(3R)crb87-5

      (Hicks et al., 1999)
      Partially rescues

      jarHsp83.PH/Scer\GAL4slbo.2.6 partially rescues jara.UAS

      (Geisbrecht and Montell, 2002)
      Comments

      The reduced viability of jar322/Df(3R)crb87-5 adults is completely rescued (without heat shock) by jarHsp83.PH.

      jarHsp83.PH cannot rescue the lethality of Df(3R)jar322 homozygotes or of Df(3R)jar322/Df(3R)crb87-4 animals, indicating that the lethality seen in these animals is not due to loss of jar function.

      (Morrison and Miller, 2008)

      jarHsp83.PH + heat shock, partially rescues border cell migration in the ovaries of jara.Scer\UAS; Scer\GAL4slbo.2.6 flies. (Flies raised at 29oC and given a 1 hour heat shock at 37oC 6-10 hours prior to dissection.)

      (Geisbrecht and Montell, 2002)

      Rescues the male sterility of jarmmw14/Df(3R)crb87-5 flies.

      (Hicks et al., 1999)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      jarHsp83.PH
      Name Synonyms
      Heat shock protein 83 promoter construct of Hicks
      (Hicks et al., 1999)
      Secondary FlyBase IDs
        References (5)