FlyBase Allele Report: Dmel\amos[UAS.cHa]

General Information

Symbol

Dmel\amos^UAS.cHa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Huang

FlyBase ID

FBal0104676

Feature type

allele

Associated gene

Dmel\amos

Associated Insertion(s)

Carried in Construct

P{UAS-amos.H}

Key Links

Transgenic product class

wild_type

(Huang et al., 2000)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Huang et al., 2000)

Mutagen

in vitro construct

(Huang et al., 2000)

Progenitor genotype

Carried in construct

P{UAS-amos.H}

Cytology

Description

UAS regulatory sequences drive expression of amos.

(Huang et al., 2000)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

amos

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy, with Scer\GAL4^sca-537.4

(Huang et al., 2000)

visible, with Scer\GAL4^hs.PB

(Huang et al., 2000)

Phenotype Manifest In

chordotonal neuron | ectopic, with Scer\GAL4^h-1J3

(Huang et al., 2000)

chordotonal neuron | ectopic, with Scer\GAL4^sca-537.4

(Huang et al., 2000)

embryonic/larval neuron | ectopic, with Scer\GAL4^sca-537.4

(Huang et al., 2000)

larval ventral cluster group multidendritic neuron, with Scer\GAL4^sca-537.4

(Huang et al., 2000)

multidendritic neuron | ectopic, with Scer\GAL4^h-1J3

(Huang et al., 2000)

multidendritic neuron | ectopic, with Scer\GAL4^sca-537.4

(Huang et al., 2000)

sensory neuron | ectopic, with Scer\GAL4^h-1J3

(Huang et al., 2000)

wing sensillum | ectopic, with Scer\GAL4^hs.PB

(Huang et al., 2000)

Detailed Description

Statement

Reference

Embryos expressing amos^Scer\UAS.cHa under the control of Scer\GAL4^h-1J3 show increased numbers of sensory neurons in segments that misexpress amos. Ectopic multiple dendritic neurons, ectopic chordotonal neurons in the lateral region and ectopic neurons in the dorsal group are induced. Embryos expressing amos^Scer\UAS.cHa under the control of Scer\GAL4^sca-537.4 have ectopic multiple dendritic (MD) neurons throughout the segments. The MD neurons in the v and v' groups are frequently misplaced at a more ventral position. A slight increase in the number of chordotonal neurons in the lateral region is also seen. Expression of amos^Scer\UAS.cHa under the control of Scer\GAL4^hs.PB using a 10 minute heat shock just after puparium formation results in ectopic bristles in the wing.

(Huang et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^sca-537.4, amos^UAS.cHa has abnormal neuroanatomy phenotype, suppressible by da[+]/da¹⁰

(Huang et al., 2000)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^sca-537.4, amos^UAS.cHa has embryonic/larval neuron | ectopic phenotype, suppressible by da[+]/da¹⁰

(Huang et al., 2000)

Suppressor of

Statement

Reference

amos^UAS.cHa/Scer\GAL4^h-1J3 is a suppressor of chordotonal neuron phenotype of ato¹

(Huang et al., 2000)

Other

Statement

Reference

Scer\GAL4^sca-537.4, amos^UAS.cHa, da^UAS.cGa has embryonic/larval neuron | ectopic phenotype

(Huang et al., 2000)

Additional Comments

Genetic Interactions

Statement

Reference

The ectopic neuron phenotype produced by expression of amos^Scer\UAS.cHa under the control of Scer\GAL4^sca-537.4 is suppressed by one copy of da¹⁰. Expression of both amos^Scer\UAS.cHa and da^Scer\UAS.cGa under the control of Scer\GAL4^sca-537.4 results in the induction of numerous elav-positive neurons. Rescues chordotonal neuron formation in odd segments in ato¹ embryos when expressed under the control of Scer\GAL4^h-1J3.

(Huang et al., 2000)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Roi^Scer\UAS.cHa

amos^Scer\UAS.cHa

amos^UAS.cHa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Huang

(Huang et al., 2000)

Secondary FlyBase IDs

References (1)

Report Sections

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