FB2024_03 , released June 25, 2024
Allele: Dmel\dlg1S48A.UAS.EGFP
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General Information
Symbol
Dmel\dlg1S48A.UAS.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0117556
Feature type
allele
Associated gene
Dmel\dlg1
Associated Insertion(s)
Carried in Construct
P{UAS-eGFP-dlg1-S48A}
Key Links
Transgenic product class
missense_variant
(Koh et al., 1999)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Koh et al., 1999)
Mutagen
in vitro construct
(Koh et al., 1999)
Progenitor genotype
Carried in construct
P{UAS-eGFP-dlg1-S48A}
Cytology
Description

UASt regulatory sequences drive expression of a mutated dlg1 coding region (carries the amino acid replacement S48A) that is tagged at the 5' end with EGFP.

(Koh et al., 1999)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dlg1
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The rescue of the dlg17 neuromuscular junction defects by dlg1S48A.Scer\UAS.T:Avic\GFP expressed under the control of Scer\GAL4unspecified is unaltered by expression of CaMKIIT287D.Scer\UAS in the postsynaptic muscles.

      (Koh et al., 1999)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      dlg1S48A.UAS.EGFP/Scer\GAL4unspecified rescues dlg17

      (Koh et al., 1999)
      Comments

      dlg1S48A.Scer\UAS.T:Avic\GFP completely rescues the ultrastructural defects seen in dlg17 neuromuscular junctions when expressed under the control of Scer\GAL4unspecified.

      (Koh et al., 1999)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      dlg1S48A.Scer\UAS.T:Avic\GFP
      dlg1S48A.UAS.EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)