FB2024_03 , released June 25, 2024
Allele: Dmel\taiUAS.cBa
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General Information
Symbol
Dmel\taiUAS.cBa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Bai
FlyBase ID
FBal0120314
Feature type
allele
Associated gene
Dmel\tai
Associated Insertion(s)
Carried in Construct
P{UAS-tai.B}
Also Known As
UAS-tai
Key Links
Transgenic product class
wild_type
(Bai et al., 2000)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Bai et al., 2000)
Mutagen
in vitro construct
(Bai et al., 2000)
Progenitor genotype
Carried in construct
P{UAS-tai.B}
Cytology
Description

UASt regulatory sequences drive expression of tai.

(Bai et al., 2000)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
tai
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of taiScer\UAS.cBa under the control of Scer\GAL4en.PU in third instar larvae leads to expansion of the posterior domain of the wing disc, particularly in the pouch, excessively folded wing tissue, and does not significantly alter the size of the anterior domain, as compared to controls. These flies die in during P-stage.

      Wing clones expressing taiScer\UAS.cBa under the control of Scer\GAL4Act.PU grow larger than age-matched control clones.

      Expression of taiScer\UAS.cBa under the control of Scer\GAL4GMR.PU moderately expands adult eye size.

      (Zhang et al., 2015)

      The expression of taiScer\UAS.cBa results in third instar larval class I abdominal dorsal multidendritic ddaD and ddaE neurons exhibiting a reduced dendritic tree and dendrite branch misrouting (expression under the control of Scer\GAL4221) and class IV abdominal dorsal multidendritic ddaC neurons exhibiting abnormal dendritic terminals (expression under the control of Scer\GAL4ppk.PG), as compared to controls.

      (Hattori et al., 2013)

      Expression of two copies of taiScer\UAS.cBa under the control of Scer\GAL4slbo.2.6 does not affect border cell migration.

      (Jang et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Enhancer of
      Statement
      Reference

      taiUAS.cBa/Scer\GAL4GMR.PU is an enhancer of eye phenotype of Scer\GAL4GMR.PU, ykiS168A.UAS.Tag:V5

      (Zhang et al., 2015)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of taiScer\UAS.cBa enhances eye overgrowth in adults, and in larval eye discs enhances early S-phase entry, leads to greater spacing between apical tufts of photoreceptor clusters, and leads to large folds of excess tissue posterior to the morphogenetic furrow, in flies expressing ykiS168A.Scer\UAS.T:Avic\GFP-YFP under the control of Scer\GAL4GMR.PU.

      Co-expression of ykiS168A.Scer\UAS.T:SV5\V5 and taiScer\UAS.cBa under the control of Scer\GAL4GMR.PU results in severe oncogenic overgrowth of the eye.

      Co-expression of sddsRNA.Scer\UAS.cUa rescues the oncogenic effect of co-expression of ykiS168A.Scer\UAS.T:SV5\V5 and taiScer\UAS.cBa under the control of Scer\GAL4GMR.PU.

      (Zhang et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4c306/taiUAS.cBa rescues tai61G1

      (Jang et al., 2009)

      Scer\GAL4c306/taiUAS.cBa rescues tai61G1

      (Bai et al., 2000)
      Comments

      Expression of taiScer\UAS.cBa under the control of Scer\GAL4c306 fully rescues the border cell migration defect of homozygous tai61G1 border cell clones.

      (Jang et al., 2009)

      Rescues the border cell migration defects seen in tai61G1 mutant clones when expressed under the control of Scer\GAL4c306.

      (Bai et al., 2000)
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      taiScer\UAS.cBa
      taiUAS.cBa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Bai
      (Bai et al., 2000)
      Secondary FlyBase IDs
        References (6)