FB2024_03 , released June 25, 2024
Allele: Dmel\skdT413
Open Close
General Information
Symbol
Dmel\skdT413
Species
D. melanogaster
Name
FlyBase ID
FBal0121622
Feature type
allele
Associated gene
Dmel\skd
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Janody et al., 2004, Treisman, 2001)
Progenitor genotype
Cytology
Description

Amino acid replacement: Q1152term.

(Treisman, 2001)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3L:21,000,290..21,000,290 [-]
Nucleotide change:

C21000290T

Amino acid change:

Q1152term | skd-PC; Q1152term | skd-PD; Q1302term | skd-PE; Q1135term | skd-PF

Reported amino acid change:

Q1152term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Treisman, 2001)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      skdT413 clones induced in the wing disc during the late second or eraly third larval instar that are confines entirely to one dorsal or ventral compartment can sometimes disrupt the dorsal-ventral boundary.

      (Janody et al., 2003)

      Clones in the eye contain few or no photoreceptors. The few that remain are found in posterior regions of the clone, and die later in development. Clone size is normal and clones do not interfere with the spread of differentiation-promoting signals. Antennal disc cell fates are also altered.

      (Treisman, 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT suppressed by
      Statement
      Reference

      skdT413 has eye disc phenotype, non-suppressible by hhUAS.cAa/Scer\GAL4ey.PH

      (Treisman, 2001)

      skdT413 has eye disc phenotype, non-suppressible by Delta::NΔECN.UAS/Scer\GAL4ey.PH

      (Treisman, 2001)

      skdT413 has eye disc phenotype, non-suppressible by cim1-4.UAS.Tag:HA/Scer\GAL4ey.PH

      (Treisman, 2001)

      skdT413 has photoreceptor neuron phenotype, non-suppressible by Delta::NΔECN.UAS/Scer\GAL4ey.PH

      (Treisman, 2001)

      skdT413 has photoreceptor neuron phenotype, non-suppressible by cim1-4.UAS.Tag:HA/Scer\GAL4ey.PH

      (Treisman, 2001)

      skdT413 has photoreceptor neuron phenotype, non-suppressible by hhUAS.cAa/Scer\GAL4ey.PH

      (Treisman, 2001)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      skdT413/skdT13 is rescued by skdUAS.cJa/Scer\GAL4da.G32

      (Janody et al., 2003)
      Partially rescued by

      skdT413/skdT13 is partially rescued by skdUAS.cJa/Scer\GAL4αTub84B.PL

      (Janody et al., 2003)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Med13T413
      (Ren et al., 2022)
      bliT413
      (Treisman, 2001)
      papT413
      skdT413
      (Ren et al., 2022, Kuang et al., 2020)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)