FB2024_03 , released June 25, 2024
Allele: Dmel\nompAGFP
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General Information
Symbol
Dmel\nompAGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0121650
Feature type
allele
Associated gene
Dmel\nompA
Associated Insertion(s)
Carried in Construct
P{nompA.GFP}
Also Known As
NompA-GFP, GFP-NompA, NOMPA::GFP
Key Links
Transgenic product class
wild_type
(Chung et al., 2001)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Chung et al., 2001)
Mutagen
in vitro construct
(Chung et al., 2001)
Progenitor genotype
nompA+t10.2
(Chung et al., 2001)
Carried in construct
P{nompA.GFP}
Cytology
Description

GFP is inserted between the predicted signal peptide and the first PAN module of nompA.

(Chung et al., 2001)
Allele components
Component
Use(s)
Regulatory region(s)
nompA
nompA_10.2_GFP
Encoded product / tool
nompA
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter or direct label
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      prepupal stage P4 -- pupal stage P6
      scolopidial dendritic cap cell
      (Todi et al., 2008)
      adult stage
      mechanosensory chaeta | distal
      (Lee et al., 2010)
      chordotonal organ of leg | subset
      (Sehadova et al., 2009)
      chordotonal organ of femur
      (Sehadova et al., 2009)
      Additional Information
      Statement
      Reference

      Expresson of the GFP-tagged, natively driven nompAT:AvicGFP shows an extended patch of labelling outlining the sheath and distal tip of dendritic cillia in tactile bristles.

      (Lee et al., 2010)
       
      Marker for
      scolopidial dendritic cap cell
      (Todi et al., 2008)
      Reflects expression of
      nompA
      (Lee et al., 2010, Sehadova et al., 2009, Todi et al., 2008)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      In otherwise wild type flies, nompAT:Avic\GFP causes some separation of the dendritic cap from bristle.

      (Chung et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      nompAGFP partially rescues nompA1/nompA2

      (Chung et al., 2001)
      Comments

      Only partially rescues behavioural and electrophysiological defects of nompA1/nompA2 mutants.

      (Chung et al., 2001)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      nompAGFP
      nompAT:Avic\GFP
      (Andrés et al., 2014)
      Name Synonyms
      Secondary FlyBase IDs
        References (12)