FB2024_03 , released June 25, 2024
Allele: Dmel\rolsA490.2M3
Open Close
General Information
Symbol
Dmel\rolsA490.2M3
Species
D. melanogaster
Name
FlyBase ID
FBal0134023
Feature type
allele
Associated gene
Dmel\rols
Associated Insertion(s)
P{lArB}rolsA490.2M3
Carried in Construct
Also Known As
rolsP1027
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Rau et al., 2001)
Progenitor genotype
Associated Insertion(s)
P{lArB}rolsA490.2M3
Cytology
Description

P{lArB} insertion approximately 70bp upstream of the rols6 (short transcript) transcription initiation site, within the second intron of rols7 (long transcript).

(Rau et al., 2001)
Allele components
Component
Use(s)
Inserted element
P{lArB}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant embryos show defects in myoblast fusion.

      (Rau et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Statement
      Reference

      rolsA490.2M3/rols[+] is a non-suppressor of lethal phenotype of Hsap\FOXO1::Hsap\PAX7UAS.cGa, Scer\GAL4Mhc.PW

      (Avirneni-Vadlamudi et al., 2012)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      rols08232

      (Rau et al., 2001)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Separable from: a second recessive lethal mutation on the chromosome.

      (Rau et al., 2001)
      Comments
      Comments

      Remobilisation of the P{PZ} element can restore viability.

      (Rau et al., 2001)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      rolsA490.2M3
      rolsP1027
      (Avirneni-Vadlamudi et al., 2012, Pütz et al., 2005, Rau et al., 2001)
      rolsP1027ber
      (Rau et al., 2001)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)