FB2024_03 , released June 25, 2024
Allele: Dmel\CRMPEP3238
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General Information
Symbol
Dmel\CRMPEP3238
Species
D. melanogaster
Name
FlyBase ID
FBal0136049
Feature type
allele
Associated gene
Dmel\CRMP
Associated Insertion(s)
P{EP}CRMPEP3238
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Pena-Rangel et al., 2002)
Progenitor genotype
Associated Insertion(s)
P{EP}CRMPEP3238
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Under free-running conditions (constant darkness), wild-type and CRMPEP3238 mutant animals exhibit similar overall activity. Period length is similar for all tested animals, indicating that the length of the circadian clock is not affected by CRMPEP3238. Compared with wild-type and heterozygous animals, significantly reduced arrhythmic power values indicating the relative strength of rhythmicity of free-running behaviours are observed among CRMPEP3238 homozygotes. Some individual CRMPsupK1 homozygotes and CRMPsupK1/Df(3R)noi-B hemizygotes lack significantly rhythmic behaviours (arrhythmic).

      Some individual CRMPEP3238 homozygotes hemizygotes lack significantly rhythmic behaviours (arrhythmic).

      (Morris et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Scer\GAL4pnr-MD237/CRMPEP3238 is a suppressor of visible phenotype of pnrMD237

      (Pena-Rangel et al., 2002)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Selected as: a P{EP} insertion line that modifies the pnrMD237/+ phenotype when expressed using Scer\GAL4pnr-MD237.

      (Pena-Rangel et al., 2002)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      CRMPEP3238
      (Morris et al., 2012)
      EP3238EP3238
      Name Synonyms
      Secondary FlyBase IDs
        References (3)