FB2024_03 , released June 25, 2024
Allele: Dmel\dlpUAS.Tag:HA
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General Information
Symbol
Dmel\dlpUAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0138279
Feature type
allele
Associated gene
Dmel\dlp
Associated Insertion(s)
Carried in Construct
P{UAS-dlp.HA}
Also Known As
UAS-Dlp-HA
Key Links
Transgenic product class
wild_type
(Giraldez et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Giraldez et al., 2002)
Mutagen
in vitro construct
(Franch-Marro et al., 2005, Giraldez et al., 2002)
Progenitor genotype
Carried in construct
P{UAS-dlp.HA}
Cytology
Description

UAS regulatory sequences drive expression of dlp tagged with Tag:HA.

(Giraldez et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dlp
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of dlpScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4ppk.PG results in third instar larval class IV abdominal dorsal multidendritic ddaC neurons exhibiting abnormal dendritic terminals, as compared to controls; expression under the control of Scer\GAL4221 results in no obvious dendrite morphology defects in class I abdominal dorsal multidendritic ddaD and ddaE neurons, as compared to controls.

      (Hattori et al., 2013)

      Expression of dlpScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4A9 results in a slight increase in wing size and chipping of the wing margin.

      (Szuperák et al., 2011)

      When dlpScer\UAS.T:Ivir\HA1 is driven by Scer\GAL4en-e16E or Scer\GAL4dpp.blk1 there is a loss of wing margin tissue. When is driven in wing clones by Scer\GAL4αTub84B.PP ectopic wing margin bristles are seen next to clones.

      (Franch-Marro et al., 2005)

      NotumScer\UAS.cGa; Scer\GAL4en-e16E flies lack some posterior wing margin bristles.

      (Kreuger et al., 2004)

      Expression of dlpScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4salm-459.2 results in scalloping of the wing.

      (Giraldez et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4elav-C155/dlpUAS.Tag:HA is a non-suppressor of abnormal neurophysiology phenotype of Sdc48/Sdc10608

      (Rawson et al., 2005)
      Other
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      dlpUAS.Tag:HA has wing margin | posterior phenotype, enhanceable by Scer\GAL4en-e16E/NotumUAS.cGa

      (Kreuger et al., 2004)
      Enhancer of
      Statement
      Reference

      Scer\GAL4en-e16E/dlpUAS.Tag:HA is an enhancer of wing margin | posterior phenotype of NotumUAS.cGa

      (Kreuger et al., 2004)
      Suppressor of
      Statement
      Reference

      Scer\GAL4elav-C155/dlpUAS.Tag:HA is a suppressor of medulla phenotype of Sdc48/Sdc10608

      (Rawson et al., 2005)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of dlpScer\UAS.T:Ivir\HA1 and ltlScer\UAS.T:Ivir\HA1,T:Zzzz\FLAG under the control of Scer\GAL4A9 disrupts wing morphogenesis and results in an approximately 42% reduction in wing size.

      (Szuperák et al., 2011)

      Expression of dlpScer\UAS.T:Ivir\HA1, under the control of Scer\GAL4elav-C155, rescues the medulla patterning defects of Sdc10608/Df(2R)48 mutants (in which Sara function has been rescued by SaraUbi.PJ). However, this expression fails to rescue the ERG defects.

      (Rawson et al., 2005)

      NotumScer\UAS.cGa; dlpScer\UAS.T:Ivir\HA1 Scer\GAL4en-e16E have a scalloped posterior wing margin.

      (Kreuger et al., 2004)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Carried in a plasmid and transfected into S2 cells.

      (Franch-Marro et al., 2005)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      dlpScer\UAS.T:Ivir\HA1
      dlpUAS.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (13)