FB2024_03 , released June 25, 2024
Allele: Dmel\ScrAntp-A41
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General Information
Symbol
Dmel\ScrAntp-A41
Species
D. melanogaster
Name
FlyBase ID
FBal0138401
Feature type
allele
Associated gene
Dmel\Scr
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Caused by aberration
    Df(3R)Antp-A41
    Cytology
    Description

    Deficiency breakpoint affecting the upstream Scr imaginal leg enhancer. The Scr transcription unit is not removed by the deficiency.

    (Southworth and Kennison, 2002)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Heterozygous males have a reduced number of sex comb teeth on the first leg. Scr1/ScrAntp-A41 males have an average of 0.3 sex comb teeth on the first leg. Scr4/ScrAntp-A41 males are recovered at 1% of expected frequency and rarely have sex comb teeth on the first legs (average is 0.08 per leg in these animals). ScrAntp-A41/ScrTpl9 males (in which the haplolethality of the Df(3R)Tpl9 chromosome has been rescued by Dp(3;3)Dfdrv1) show 13% viability and have an average of 1.8 sex comb teeth per first leg. ScrLIN/ScrAntp-A41 males have an average of 2.8 sex comb teeth on the first leg (compared to 10.8 per leg in wild type).

        (Southworth and Kennison, 2002)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        NOT Enhanced by
        Statement
        Reference

        ScrAntp-A41/ScrTpl9 has sex comb phenotype, non-enhanceable by z11G3

        (Southworth and Kennison, 2002)

        ScrAntp-A41/ScrTpl9 has sex comb phenotype, non-enhanceable by z1

        (Southworth and Kennison, 2002)

        ScrAntp-A41/ScrTpl9 has sex comb phenotype, non-enhanceable by za

        (Southworth and Kennison, 2002)
        NOT suppressed by
        Statement
        Reference

        ScrAntp-A41/ScrTpl9 has sex comb phenotype, non-suppressible by z11G3

        (Southworth and Kennison, 2002)

        ScrAntp-A41/ScrTpl9 has sex comb phenotype, non-suppressible by z1

        (Southworth and Kennison, 2002)

        ScrAntp-A41/ScrTpl9 has sex comb phenotype, non-suppressible by za

        (Southworth and Kennison, 2002)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        The average number of sex comb teeth per first leg in ScrTpl9/ScrAntp-A41 males (in which the haplolethality of the Df(3R)Tpl9 chromosome has been rescued by Dp(3;3)Dfdrv1) is not affected if they are also carrying z1, za or z11G3.

        (Southworth and Kennison, 2002)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        ScrAntp-A41
        Name Synonyms
        Secondary FlyBase IDs
          References (1)