FlyBase Allele Report: Dmel\hry[UAS.cIa]

General Information

Symbol

Dmel\hry^UAS.cIa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Ish-Horowicz

FlyBase ID

FBal0141097

Feature type

allele

Associated gene

Dmel\hry

Associated Insertion(s)

Carried in Construct

P{UAS-hry.I}

Also Known As

UAS-hairy

Key Links

Transgenic product class

wild_type

(Myat and Andrew, 2002)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Myat and Andrew, 2002)

Mutagen

in vitro construct

(Myat and Andrew, 2002)

Progenitor genotype

Carried in construct

P{UAS-hry.I}

Cytology

Description

UAS regulatory sequences drive expression of wild-type h.

(Myat and Andrew, 2002)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

hry

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^GMR.PF

(Jennings et al., 2008)

visible, with Scer\GAL4^MD-638

(Molnar et al., 2006)

Phenotype Manifest In

eye, with Scer\GAL4^GMR.PF

(Jennings et al., 2008)

pigment cell, with Scer\GAL4^GMR.PF

(Jennings et al., 2008)

wing, with Scer\GAL4^MD-638

(Molnar et al., 2006)

wing vein, with Scer\GAL4^MD-638

(Molnar et al., 2006)

Detailed Description

Statement

Reference

Expression of h^Scer\UAS.cIa under the control of Scer\GAL4^GMR.PF leads to a marked reduction in eye size and some loss of eye pigmentation.

(Jennings et al., 2008)

Expression of h^Scer\UAS.cIa under the control of Scer\GAL4^MD-638 results in loss of wing veins and reduced wing size.

(Molnar et al., 2006)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressed by

Statement

Reference

hry^UAS.cIa has eye phenotype, suppressible by gro[+]/gro^MBB

(Jennings et al., 2008)

hry^UAS.cIa has eye phenotype, suppressible by gro^MB6/gro[+]

(Jennings et al., 2008)

hry^UAS.cIa has eye phenotype, suppressible by gro^MB36/gro[+]

(Jennings et al., 2008)

hry^UAS.cIa has eye phenotype, suppressible by gro^MB18/gro[+]

(Jennings et al., 2008)

hry^UAS.cIa has eye phenotype, suppressible by gro^MB33/gro[+]

(Jennings et al., 2008)

hry^UAS.cIa has eye phenotype, suppressible by gro^MB5/gro[+]

(Jennings et al., 2008)

hry^UAS.cIa has eye phenotype, suppressible by gro^MB12/gro[+]

(Jennings et al., 2008)

hry^UAS.cIa has eye phenotype, suppressible by gro^MBD/gro[+]

(Jennings et al., 2008)

hry^UAS.cIa has eye phenotype, suppressible by gro[+]/gro^MB19

(Jennings et al., 2008)

hry^UAS.cIa has eye phenotype, suppressible by gro^MB21/gro[+]

(Jennings et al., 2008)

hry^UAS.cIa has eye phenotype, suppressible by gro^MB41/gro[+]

(Jennings et al., 2008)

hry^UAS.cIa has eye phenotype, suppressible by gro^MB30/gro[+]

(Jennings et al., 2008)

hry^UAS.cIa has eye phenotype, suppressible by gro^MB11/gro[+]

(Jennings et al., 2008)

hry^UAS.cIa has eye phenotype, suppressible by gro[+]/gro^MB31

(Jennings et al., 2008)

hry^UAS.cIa has eye phenotype, suppressible by gro^MB35/gro[+]

(Jennings et al., 2008)

hry^UAS.cIa has eye phenotype, suppressible by gro^MB25/gro[+]

(Jennings et al., 2008)

hry^UAS.cIa has eye phenotype, suppressible by gro^MB27/gro[+]

(Jennings et al., 2008)

hry^UAS.cIa has eye phenotype, suppressible by gro^MB34/gro[+]

(Jennings et al., 2008)

hry^UAS.cIa has eye phenotype, suppressible by gro[+]/gro^MB42

(Jennings et al., 2008)

hry^UAS.cIa has eye phenotype, suppressible by gro^MB13/gro[+]

(Jennings et al., 2008)

hry^UAS.cIa has eye phenotype, suppressible by gro^MB37/gro[+]

(Jennings et al., 2008)

hry^UAS.cIa has eye phenotype, suppressible by gro[+]/gro^MB15

(Jennings et al., 2008)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescues

Scer\GAL4^fkh.PH/hry^UAS.cIa partially rescues hry⁶⁷⁴

(Myat and Andrew, 2002)

Comments

Expression of h^Scer\UAS.cIa under the control of Scer\GAL4^fkh.PH partially rescues the salivary gland defects of h⁶⁷⁴ homozygous embryos; 75% of salivary glands are normal (have elongated, unbranched lumens) and 25% have elongated, expanded lumens in the rescued embryos.

(Myat and Andrew, 2002)

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

36529

w^*; P{UAS-hry.I}2

Notes on Origin

Discoverer

D. Ish-Horowicz

(Myat and Andrew, 2002)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

h^Scer\UAS.cIa

h^UAS.cIa

hry^UAS.cIa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Ish-Horowicz

(Myat and Andrew, 2002)

Secondary FlyBase IDs

References (3)

Report Sections

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