FlyBase Allele Report: Dmel\Mekk1[UAS.cIa]

General Information

Symbol

Dmel\Mekk1^UAS.cIa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Inoue

FlyBase ID

FBal0141667

Feature type

allele

Associated gene

Dmel\Mekk1

Associated Insertion(s)

Carried in Construct

P{UAS-Mekk1.I}

Key Links

Transgenic product class

wild_type

(Inoue et al., 2001)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Inoue et al., 2001)

Mutagen

in vitro construct

(Inoue et al., 2001)

Progenitor genotype

Carried in construct

P{UAS-Mekk1.I}

Cytology

Description

Expression of the Mekk1 coding region is governed by UASt regulatory sequences.

(Inoue et al., 2001)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Mekk1

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^Bx-MS1096

(Sano et al., 2005)

Phenotype Manifest In

wing, with Scer\GAL4^Bx-MS1096

(Sano et al., 2005)

Detailed Description

Statement

Reference

Expression of Mekk1^Scer\UAS.cIa in the wing disc, under the control of Scer\GAL4^Bx-MS1096, leads to severe defects in wing formation.

(Sano et al., 2005)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Mekk1^UAS.cIa, Scer\GAL4^Bx-MS1096 has visible phenotype, suppressible by Atf-2^bZIP.UAS, Scer\GAL4^Bx-MS1096

(Sano et al., 2005)

Suppressor of

Statement

Reference

Mekk1^UAS.cIa, Scer\GAL4^hs.PB is a suppressor | partially of abnormal osmotic stress response phenotype of Atf-2^bZIP.UAS, Scer\GAL4^hs.PB

(Sano et al., 2005)

Phenotype Manifest In

Suppressed by

Statement

Reference

Mekk1^UAS.cIa, Scer\GAL4^Bx-MS1096 has wing phenotype, suppressible by Atf-2^bZIP.UAS, Scer\GAL4^Bx-MS1096

(Sano et al., 2005)

Additional Comments

Genetic Interactions

Statement

Reference

Coexpression of Atf-2^{bZIP.Scer\UAS} with Mekk1^Scer\UAS.cIa, under the control of Scer\GAL4^Bx-MS1096, results in a partial suppression of the Mekk1^Scer\UAS.cIa-induced wing phenotype.

Coexpression of Mekk1^Scer\UAS.cIa with Atf-2^{bZIP.Scer\UAS} partially suppresses the Scer\GAL4^hs.PB>Atf-2^{bZIP.Scer\UAS} salt sensitivity.

(Sano et al., 2005)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Mekk1^Scer\UAS.cIa

Mekk1^UAS.cIa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Inoue

(Inoue et al., 2001)

Secondary FlyBase IDs

References (4)

Report Sections

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