FB2024_03 , released June 25, 2024
Allele: Dmel\wdb12
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General Information
Symbol
Dmel\wdb12
Species
D. melanogaster
Name
FlyBase ID
FBal0143113
Feature type
allele
Associated gene
Dmel\wdb
Associated Insertion(s)
P{EP}EP3559
Carried in Construct
Also Known As
wdbEP3559
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Hannus et al., 2002)
P-element activity
(Hannus et al., 2002)
Progenitor genotype
P{EP}EP3559
(Hannus et al., 2002)
Associated Insertion(s)
P{EP}EP3559
Cytology
Description

Mutation in a wdb splice site. In addition, the P{EP}wdbEP3559 insertion is still present on the chromosome.

(Hannus et al., 2002)
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:27,567,415..27,567,415 [-]
Comment:

An unspecified mutation in the splice donor site. The splice site mutation has been arbitrarily mapped by a FlyBase curator to the first base of the splice donor site.

(Hannus et al., 2002)
transposable_element_insertion_site
3R:27,582,191..27,582,191 [-]
(Yeh et al., 2010, Hannus et al., 2002)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of wdb12 under the control of Scer\GAL4ap-md544 (using the P{EP}wdbEP3559 insertion) results in an average of 4+/-2 cells in the fifth wing cell having a multiple wing hair phenotype. Homozygous wdb12 clones have no effect in hair formation or polarity.

      (Hannus et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      wdb12, Scer\GAL4Eq is a non-suppressor of macrochaeta phenotype of Hsap\MAPTUAS.cWa, Scer\GAL4Eq

      (Yeh et al., 2010)

      wdb12, Scer\GAL4Eq is a non-suppressor of sensory organ cell phenotype of Hsap\MAPTUAS.cWa, Scer\GAL4Eq

      (Yeh et al., 2010)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      The Hsap\MAPTScer\UAS.cWa induced bristle loss phenotype is not suppressed by co-expression of wdb12 (both under the control of Scer\GAL4Eq1).

      (Yeh et al., 2010)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      wdb12
      (Hannus et al., 2002)
      wdb12
      Name Synonyms
      Secondary FlyBase IDs
        References (2)