FB2024_03 , released June 25, 2024
Allele: Dmel\CycAUAS.Tag:HA
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General Information
Symbol
Dmel\CycAUAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0148094
Feature type
allele
Associated gene
Dmel\CycA
Associated Insertion(s)
Carried in Construct
P{UAS-CycA.HA}
Key Links
Transgenic product class
wild_type
(Grosskortenhaus and Sprenger, 2002)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Grosskortenhaus and Sprenger, 2002)
Mutagen
in vitro construct
(Grosskortenhaus and Sprenger, 2002)
Progenitor genotype
Carried in construct
P{UAS-CycA.HA}
Cytology
Description

Expression of CycA tagged with Tag:HA is under the control of UAS sequences.

(Grosskortenhaus and Sprenger, 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
CycA
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Males expressing CycAScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 show no defects in centrosome or spindle orientation in germline stem cells.

      (Yuan et al., 2012)

      Flies expressing CycAScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4da.G32 are recovered at low frequency and have rough eyes, bristle defects and reduced viability. Expression of CycAScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4hs.2sev results in ectopic S phases.

      (Dienemann and Sprenger, 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Coexpression of dltdsRNA.Scer\UAS with CycAScer\UAS.T:Ivir\HA1, under the control of Scer\GAL4ptc-559.1, has little or no effect on the dltdsRNA.Scer\UAS wing cell phenotype.

      (Pielage et al., 2003)

      CycAScer\UAS.T:Ivir\HA1; Scer\GAL4prd.RG1 suppresses the mitotic block due to Rca12/Rca13, in alternate segments.

      (Grosskortenhaus and Sprenger, 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4prd.RG1/CycAUAS.Tag:HA partially rescues CycAC8LR1

      (Dienemann and Sprenger, 2004)
      Comments

      Expression of CycAScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4prd.RG1 partially rescues the cell division defects seen in CycAC8LR1 embryos; there is an increase in cell number and a reduction in cell size in the Scer\GAL4prd.RG1 expression domain.

      (Dienemann and Sprenger, 2004)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Axel Dienemann

      (Grosskortenhaus and Sprenger, 2002)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      CycAScer\GAL4.T:Ivir\HA1
      CycAScer\UAS.T:Ivir\HA1
      CycAUAS.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (5)