FB2024_03 , released June 25, 2024
Allele: Dmel\Inx2UAS.cBa
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General Information
Symbol
Dmel\Inx2UAS.cBa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Bauer
FlyBase ID
FBal0151826
Feature type
allele
Associated gene
Dmel\Inx2
Associated Insertion(s)
Carried in Construct
P{UAS-Inx2.B}
Also Known As
UAS-inx2
Key Links
Transgenic product class
wild_type
(Bauer et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Bauer et al., 2002)
Mutagen
in vitro construct
(Bauer et al., 2002)
Progenitor genotype
Carried in construct
P{UAS-Inx2.B}
Cytology
Description

UAS regulatory sequences drive expression of Inx2.

(Bauer et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Inx2
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of inx2Scer\UAS.cBa in early blastoderm embryos, under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16, results in massive cell death in all epithelia of the embryo.

      (Bauer et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Expression of inx2Scer\UAS.cBa, under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16, in a BacA\p35Scer\UAS.cHa background (which prevents cell death) results in multilayering and a variation in cell size in the embryos.

      (Bauer et al., 2004)
      Complementation and Rescue Data
      Rescues

      Inx2UAS.cBa/Scer\GAL4arm.PS rescues Inx2G0016

      (Bauer et al., 2002)

      Inx2UAS.cBa/Scer\GAL4da.G32 rescues Inx2G0016

      (Bauer et al., 2002)
      Partially rescues

      Inx2UAS.cBa/Scer\GAL4hs.PU partially rescues Inx2FA42

      (Mukai et al., 2011)
      Comments

      Expression of Inx2Scer\UAS.cBa under the control of Scer\GAL4hs.PU partially rescues the sterility of Inx2FA42 homozygous females: 51.9% of ovaries are able to produce mature eggs in the rescued females.

      (Mukai et al., 2011)

      The embryonic defects and mutant larval feeding phenotype of inx2G0016 animals is rescued by expression of inx2Scer\UAS.cBa under the control of Scer\GAL4arm.PS or Scer\GAL4da.G32.

      (Bauer et al., 2002)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Inx2Scer\UAS.cBa
      Inx2UAS.cBa
      inx2Scer\UAS.cBa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Bauer
      (Bauer et al., 2002)
      Secondary FlyBase IDs
        References (6)