FB2024_03 , released June 25, 2024
Allele: Dmel\bazS151A.S1085A.UASp.GFP
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General Information
Symbol
Dmel\bazS151A.S1085A.UASp.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0152104
Feature type
allele
Associated gene
Dmel\baz
Associated Insertion(s)
Carried in Construct
P{UASp-baz.S151A.S1085A}
Also Known As
UASp-BazS151AS1085A-GFP
Key Links
Transgenic product class
missense_variant
(Benton and St. Johnston, 2003)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Benton and St. Johnston, 2003)
Mutagen
in vitro construct
(Benton and St. Johnston, 2003)
Progenitor genotype
bazUASp.GFP
(Benton and St. Johnston, 2003)
Carried in construct
P{UASp-baz.S151A.S1085A}
Cytology
Description

Construct: Amino acid replacement: S151A. Amino acid replacement: S1085A.

(Benton and St. Johnston, 2003)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
baz
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of bazS151A.S1085A.Scer\UAS.P\T.T:Avic\GFP under the control of Scer\GAL4CY2 in the follicle cells results in apical constriction of the cells in 75% of cases.

      (Claret et al., 2014)

      Expression of bazS151A.S1085A.Scer\UAS.P\T.T:Avic\GFP under the control of Scer\GAL4unspecified in the oocyte results in a high density of microtubules throughout the oocyte at stage 9, in contrast to the anterior-to-posterior gradient seen in the wild type at this stage.

      (Doerflinger et al., 2010)

      Expression of bazS151A.S1085A.Scer\UAS.P\T.T:Avic\GFP under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16 results in mis-positioning of the nucleus in the oocyte, and eggs produced by these females are ventralised.

      (Gervais et al., 2008)

      Expression of bazS151A.S1085A.Scer\UAS.P\T.T:Avic\GFP under the control of Scer\GAL4c306 results in border follicle cell detachment defects, with many border cells showing no migration. In addition, border cells showing incomplete migration are seen.

      (McDonald et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      baz4 sdtXP follicle cell clones expressing bazS151A.S1085A.Scer\UAS.P\T.T:Avic\GFP under the control of Scer\GAL4e22c lose their epithelial organisation and form multilayers of cells.

      (Benton and St. Johnston, 2003)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      bazS151A.S1085A.Scer\UAS.P\T.T:Avic\GFP
      bazS151A.S1085A.UASp.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (11)