FB2024_03 , released June 25, 2024
Allele: Dmel\DIP1c.UAS
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General Information
Symbol
Dmel\DIP1c.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0152654
Feature type
allele
Associated gene
Dmel\DIP1
Associated Insertion(s)
Carried in Construct
P{UAS-DIP1.c}
Also Known As
UAS-DIP1-c
Key Links
Transgenic product class
cDNA
(DeSousa et al., 2003)
wild_type
(DeSousa et al., 2003)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(DeSousa et al., 2003)
wild_type
(DeSousa et al., 2003)
Mutagen
in vitro construct
(DeSousa et al., 2003)
Progenitor genotype
Carried in construct
P{UAS-DIP1.c}
Cytology
Description

UASt regulatory sequences drive expression of the DIP1-c cDNA.

(DeSousa et al., 2003)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
DIP1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing DIP1c.Scer\UAS under the control of Scer\GAL4Bx-MS1096 show a dramatic reduction in wing size and the wings have a thicker, shriveled appearance. The change in wing size is due to a change in cell number, not in cell size. In less than 2% of cases, bifurcated wings are seen. Wing veins and wing margin bristles are lost, although some heavy bristles are clustered proximal to the notum and at the most distal edge of the wing. The halteres show a range of defects compared to wild type; most have a misshaped capitellum and about 10% are also bifurcated.

      (Bondos et al., 2004)

      Escapers expressing DIP1c.Scer\UAS under the control of Scer\GAL4ey.PH show a number of phenotypes including the duplication of antennal palps and a deletion of arista and the ectopic expression of head capsule tissue in presumptive eye tissue.

      (DeSousa et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Ubxbx-34e/+ flies expressing DIP1c.Scer\UAS under the control of Scer\GAL4Bx-MS1096 have long bristles along the entire surface of the haltere.

      (Bondos et al., 2004)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      DIP1c.Scer\UAS
      DIP1c.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)