When pod1^{Scer\UAS.T:Avic\GFP,T:Hsap\MYC} is driven by Scer\GAL4^elav.PLu multiple, severe axon guidance defects are seen in all axons. 23.3% 44.1% and 56.3% of embryos exhibit defects in the ISN, SNa and ISNb neurons respectively. The ISN exhibits defasciculation, overbranching, and choice point abnormalities. SNa often show missong or misplaced branches, abnormal defasciculation, and defective trajectories. ISNb often frequently arrest and fail to innervate targets in the ventral musculature, remain fasciculated with ISN, or take abnormal trajectories. When pod1^{Scer\UAS.T:Avic\GFP,T:Hsap\MYC} (driven by Scer\GAL4^Act) is over expressed in S2 cells a dose dependent remodelling of cell shape is seen. Cells expressing high levels of pod1^{Scer\UAS.T:Avic\GFP,T:Hsap\MYC} extend long, neurite-like projections that are sometimes branched. These were highly dynamic, displaying behaviours such as growth and extension, lateral movement along the cell surface, retrograde flow, and catastrophic collapse and retraction. These processes are rich in actin bundles. These processes are not dependent on microtubules.