FlyBase Allele Report: Dmel\XNP[UY3132]

General Information

Symbol

Dmel\XNP^UY3132

Species

D. melanogaster

Name

FlyBase ID

FBal0155675

Feature type

allele

Associated gene

Dmel\XNP

Associated Insertion(s)

P{Mae-UAS.6.11}XNP^UY3132

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Nicolai et al., 2003)

Progenitor genotype

Associated Insertion(s)

P{Mae-UAS.6.11}XNP^UY3132

Cytology

Description

Insertion site maps to -261bp of the known/supposed transcription start site.

(Nicolai et al., 2003)

Allele components

Component

Use(s)

Inserted element

P{Mae-UAS.6.11}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy, with Scer\GAL4^7B

(Nicolai et al., 2003)

partially lethal - majority die, with Scer\GAL4^Act5C.PU

(Valadez-Graham et al., 2012)

Phenotype Manifest In

adult mushroom body, with Scer\GAL4^7B

(Nicolai et al., 2003)

Kenyon cell, with Scer\GAL4^7B

(Nicolai et al., 2003)

Detailed Description

Statement

Reference

When expression is driven by Scer\GAL4^7B, XNP^UY3132 shows a mushroom body Class I phenotype; neuron number defects.

(Nicolai et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

XNP^UY3132/Scer\GAL4^pnr-MD237 is an enhancer of visible phenotype of pnr^MD237

(Valadez-Graham et al., 2012)

Other

Statement

Reference

Scer\GAL4^Act5C.PU, XNP^UY3132, pnr^VX6 has lethal phenotype

(Valadez-Graham et al., 2012)

Phenotype Manifest In

Enhancer of

Statement

Reference

XNP^UY3132/Scer\GAL4^pnr-MD237 is an enhancer of adult thorax | dorsal phenotype of pnr^MD237

(Valadez-Graham et al., 2012)

XNP^UY3132/Scer\GAL4^455.2 is an enhancer of scutellum phenotype of pnr¹

(Valadez-Graham et al., 2012)

XNP^UY3132/Scer\GAL4^455.2 is an enhancer of scutellum phenotype of pnr^VX6

(Valadez-Graham et al., 2012)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of XNP^UY3132 under the control of Scer\GAL4^pnr-MD237 enhances the mild thoracic cleft phenotype seen in pnr^MD237 heterozygotes.

Expression of XNP^UY3132 under the control of Scer\GAL4^455.2 enhances the penetrance of the scutellar phenotypes seen in pnr¹ and in pnr^VX6 heterozygotes.

(Valadez-Graham et al., 2012)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

7355

y¹ w^67c23; P{Mae-UAS.6.11}XNP^UY3132

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

XNP^UY3132

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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