FB2024_03 , released June 25, 2024
Allele: Scer\GAL4amos.PZ
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General Information
Symbol
Scer\GAL4amos.PZ
Species
S. cerevisiae
Name
absent MD neurons and olfactory sensilla promoter construct of zur Lage
FlyBase ID
FBal0155848
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{amos-GAL4.Z}
Also Known As
amos-Gal4
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(zur Lage et al., 2003)
Progenitor genotype
Carried in construct
P{amos-GAL4.Z}
Cytology
Description

A 3.6kb fragment upstream of the amos start sites regulates expression of a GAL4 driver.

(zur Lage et al., 2003)
Allele components
Component
Use(s)
Regulatory region(s)
amos
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      prepupal stage P3
      external sensory organ precursor cell | subset of presumptive third segment of antenna
      (Chai et al., 2019)
      prepupal stage P4 -- pupal stage P5
      external sensory organ precursor cell | subset of presumptive third segment of antenna
      (zur Lage et al., 2003)
      olfactory sensory organ | precursor of presumptive third segment of antenna
      (zur Lage et al., 2003)
      adult stage
      antennal olfactory receptor neuron of basiconic sensillum | subset
      (Okumura et al., 2016)
      antennal olfactory receptor neuron of trichoid sensillum | subset
      (Okumura et al., 2016)
      adult olfactory receptor neuron Or19
      (Kaur et al., 2019)
      adult olfactory receptor neuron Or43a
      (Kaur et al., 2019)
      adult olfactory receptor neuron Or47b
      (Kaur et al., 2019)
      Additional Information
      Statement
      Reference

      ScerGAL4amos.PZ drives expression in a subset of olfactory sensory organ precursor cells located in the presumptive third antennal segment of the antennal disc starting at 4 hours APF; these precursors go on to become basiconic and trichoid sensilla.

      (Chai et al., 2019)

      ScerGAL4amos.PZ-expressing neurons arrive at the antennal lobes at 28 hours APF.

      (Okumura et al., 2016)
       
      Marker for
      Reflects expression of
      amos
      (Okumura et al., 2016, zur Lage et al., 2003)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ablation of amos-positive olfactory receptor neurons by expressing Rcom\RAUAS.FRT under the control of Scer\GAL4amos.PZ together with Scer\FLP1ey.PN leads to the disorganization of the anterior antennal lobe and fuzzy glomerular borders, without affecting the formation of posterior glomeruli.

      (Okumura et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      amosUAS.cGa/Scer\GAL4amos.PZ partially rescues amos1/Df(2L)M36F-S6

      (Holohan et al., 2006)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Scer\GAL4amos.PZ
      Name Synonyms
      absent MD neurons and olfactory sensilla promoter construct of zur Lage
      (zur Lage et al., 2003)
      Secondary FlyBase IDs
        References (6)