rhabdomere & actin filament, with MoeRNAi.327-775.UAS, Scer\GAL4GMR.PF
rhabdomere & actin filament, with MoeRNAi.327-775.UAS, Scer\GAL4hs.PB
Moe818-1326.dsRNA.Scer\UAS; Moe327-775.dsRNA.Scer\UAS; Scer\GAL4MD-638 flies have wing phenotypes similar to those due to Moec858 : wings are small (in particular, they are severely shortened along the proximal-distal axis); vesicles form between the dorsal and ventral surfaces of the wing; veination is defective. In the late third instar wing disc, there is ectopic folding of the disc epithelium. This folding sometimes extends back under the disc making transverse sections multi-layered.
Rhabdomeres in the eyes of Moe818-1326.dsRNA.Scer\UAS; Moe327-775.dsRNA.Scer\UAS; Scer\GAL4hs.PB flies heat shocked at approximately 50% pupal development have a disorganised actin cytoskeleton and reduced, irregular microvillar fields. Apical differentiation and organisation of the actin cytoskeleton is severely disrupted in the photoreceptors of Moe818-1326.dsRNA.Scer\UAS; Moe327-775.dsRNA.Scer\UAS; Scer\GAL4GMR.PF animals. Microvillar and stalk membranes in these photoreceptors are distinct but jumbled. Despite these defects, epithelial integrity is maintained, and photoreceptor adherens-junctions appear normal.