FB2024_03 , released June 25, 2024
Allele: Dmel\E(ftz)42364236
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General Information
Symbol
Dmel\E(ftz)42364236
Species
D. melanogaster
Name
FlyBase ID
FBal0176220
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Embryos derived from homozygous female germline clones are normal.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference

E(ftz)4236[+]/E(ftz)42364236 is an enhancer | maternal effect of partially lethal | heat sensitive phenotype of ftz5/ftz13

Phenotype Manifest In
Suppressor of
Statement
Reference

E(ftz)4236[+]/E(ftz)42364236 is a suppressor of embryonic segment phenotype of ftz5/ftz13

Additional Comments
Genetic Interactions
Statement
Reference

E(ftz)42364236 dominantly enhances the lethality of ftz5/ftz13 animals at 26.5oC (fewer animals survive to adulthood). This interaction involves both a zygotic effect and a weak maternal effect. E(ftz)42364236 dominantly suppresses the segmentation defects seen in ftz5/ftz13 embryos at 27.5oC; 39.0% of the embryos have segment defects and 1.2% have at least 3 ftz-dependent segments affected.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Selected as: a dominant enhancer of the lethality of ftz5/ftz13 at 26.5oC.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
E(ftz)42364236
Name Synonyms
Secondary FlyBase IDs
    References (1)