FB2024_03 , released June 25, 2024
Allele: Dmel\midUAS.cQb
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General Information
Symbol
Dmel\midUAS.cQb
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct b of Qian
FlyBase ID
FBal0178886
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-nmr2, UAS-mid
Key Links
Nature of the Allele
Progenitor genotype
Carried in construct
Cytology
Description

UASt sequences drive expression of full-length mid (sequence from clone RE27439).

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Females expressing ectopic midScer\UAS.cQb throughout the follicular epithelium under the control of Scer\GAL4T155 produce eggs with no dorsal appendages.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Additional Comments
Genetic Interactions
Statement
Reference

The increase in heart arrest/fibrillation upon electrical pacing that is seen in pnrVX6/+ adults is ameliorated by expression of midScer\UAS.cQb under the simultaneous control of both Scer\GAL4twi.PG and Scer\GAL4how-24B. The cardiac arrhythmias seen in pnrVX6/+ adults are also rescued in these animals.

The increase in heart arrest/fibrillation upon electrical pacing that is seen in pnrVX6/+ adults is ameliorated by expression of midScer\UAS.cQb under the control of either Scer\GAL4Mef2.PR or Scer\GAL4tin.CΔ4. The cardiac arrhythmias seen in pnrVX6/+ adults are also rescued in animals expressing midScer\UAS.cQb under the control of Scer\GAL4tin.CΔ4.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
midScer\UAS.cQb
midUAS.cQb
Name Synonyms
Saccharomyces cerevisiae UAS construct b of Qian
Secondary FlyBase IDs
    References (6)