FB2024_03 , released June 25, 2024
Allele: Dmel\baboa.UAS
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General Information
Symbol
Dmel\baboa.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0190569
Feature type
allele
Associated gene
Dmel\babo
Associated Insertion(s)
Carried in Construct
P{UAS-babo.a}
Also Known As
UAS-babo-a
Key Links
Transgenic product class
wild_type
(Zheng et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Zheng et al., 2006)
Mutagen
in vitro construct
(Zheng et al., 2006)
Progenitor genotype
Carried in construct
P{UAS-babo.a}
Cytology
Description

UAS regulatory sequences drive expression of the a isoform of babo.

(Zheng et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
babo
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of dawScer\UAS.cSa, baboa.Scer\UAS and babob.Scer\UAS in the wing under the control of Scer\GAL4A9 does not result in wing vein patterning defects.

      (Jensen et al., 2009)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4Act.PU, Ecol\lexADBD.UAS, Hsim\VP16AD.C1a.ort, baboa.UAS rescues babo9

      (Ting et al., 2014)

      Scer\GAL4insc-Mz1407, babob.UAS, baboa.UAS rescues babo32/babo26

      (Zhu et al., 2008)

      babob.UAS, Scer\GAL4wor.PA, baboa.UAS rescues babo32/babo26

      (Zhu et al., 2008)

      baboa.UAS/Scer\GAL4Act5C.PP rescues babo52

      (Ting et al., 2007)

      baboa.UAS/Scer\GAL4Act5C.PP rescues babo9

      (Ting et al., 2007)
      Partially rescues

      Scer\GAL4Tab2-201Y/baboa.UAS partially rescues babo9

      (Zheng et al., 2006)
      Fails to rescue

      babob.UAS, baboa.UAS, Scer\GAL4ey.PH fails to rescue babo32/babo26

      (Zhu et al., 2008)

      babob.UAS, Scer\GAL4repo, baboa.UAS fails to rescue babo32/babo26

      (Zhu et al., 2008)

      Scer\GAL4da.G32/baboa.UAS fails to rescue babo26/babo52

      (Zhu et al., 2008)
      Comments

      Expression of baboa.Scer\UAS under the control of Scer\GAL4Act.PU, targeted to the Tm20 neurons using Ecol\lexADBD.Scer\UAS.T:Zzzz\ZipRREEL and Hsim\VP16C1a.AD.ort.T:Zzzz\ZipEERRL, rescues the dendritic phenotype seen in babo9 mutant Tm neuron clones.

      (Ting et al., 2014)

      Expression of baboa.Scer\UAS under the control of Scer\GAL4da.G32 does not rescue the photoreceptor axon targeting defects and small brain phenotype of babo26/babo52 mutants.

      Co-expression of both baboa.Scer\UAS and babob.Scer\UAS under the control of Scer\GAL4ey.PH or Scer\GAL4repo does not rescue the photoreceptor axon targeting defects of babo26/babo32 mutants.

      Co-expression of both baboa.Scer\UAS and babob.Scer\UAS under the control of Scer\GAL41407 or Scer\GAL4wor.PA rescues the brain size and photoreceptor axon targeting defects of babo26/babo32 mutants.

      (Zhu et al., 2008)

      Expression of baboa.Scer\UAS, under the control of Scer\GAL4Tab2-201Y, in babo9 mutant γ neurons fully rescues mushroom body remodeling defects. Scer\GAL4Tab2-201Y>baboa.Scer\UAS expression provides a significant but incomplete rescue of dorsal cluster neuron defects.

      (Zheng et al., 2006)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      baboa.Scer\UAS
      baboa.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (9)