FlyBase Allele Report: Dmel\Prx2[UAS.cHa]

General Information

Symbol

Dmel\Prx2^UAS.cHa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Ha

FlyBase ID

FBal0191202

Feature type

allele

Associated gene

Dmel\Prx2

Associated Insertion(s)

Carried in Construct

P{UAS-Prx2.H}

Also Known As

UAS-jafrac1

Key Links

Transgenic product class

wild_type

(Ha et al., 2005)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Ha et al., 2005)

Mutagen

in vitro construct

(Ha et al., 2005, Ha et al., 2005)

Progenitor genotype

Carried in construct

P{UAS-Prx2.H}

Cytology

Description

UAS regulatory sequences drive expression of Jafrac1.

(Ha et al., 2005)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Prx2

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal chemosensory behavior, with Scer\GAL4^da.PU

(Du et al., 2016)

short lived | conditional, with Scer\GAL4^da.G32

(Nam et al., 2012)

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of Jafrac1^Scer\UAS.cHa under the control of Scer\GAL4^da.PU results in lack of uracil-dependent defecation.

(Du et al., 2016)

Flies expressing Jafrac1^Scer\UAS.cHa under the control of Scer\GAL4^da.G32 show 15% mortality within 24 hours of mild wounding in 7-8 days old adults compared to 1% in controls. The mortality rate is increased to ~50% in response to more severe wounding.

(Nam et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Prx2^UAS.cHa, Scer\GAL4^elav-C155 is a suppressor of short lived phenotype of Hsap\HTT^Q93.ex1.UAS, Scer\GAL4^elav-C155

(Besson et al., 2015)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

The reduced survival rate after natural infection with "Ecc-15" (P.carotovorum.carotovorum) that is seen in flies expressing Irc^{dsRNA.Scer\UAS} under the control of Scer\GAL4^da.G32 is slightly rescued by co-expression of Jafrac1^Scer\UAS.cHa.

(Ha et al., 2005)

Xenogenetic Interactions

Statement

Reference

Co-expression of Jafrac1^Scer\UAS.cHa significantly extends the lifespan of flies expressing Scer\GAL4^elav-C155>Hsap\HTT^{Q93.ex1p.Scer\UAS}.

(Besson et al., 2015)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Jafrac1^Scer\UAS.cHa

Jafrac1^UAS.cHa

Prx2^UAS.cHa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Ha

(Ha et al., 2005)

Secondary FlyBase IDs

References (5)

Report Sections

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