FB2024_03 , released June 25, 2024
Allele: Dmel\Tdc2UAS.cCb
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General Information
Symbol
Dmel\Tdc2UAS.cCb
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct b of Cole
FlyBase ID
FBal0191488
Feature type
allele
Associated gene
Dmel\Tdc2
Associated Insertion(s)
Carried in Construct
P{UAS-Tdc2.C}
Also Known As
UAS-Tdc2
Key Links
Transgenic product class
wild_type
(Cole et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Cole et al., 2005)
Mutagen
in vitro construct
(Cole et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-Tdc2.C}
Cytology
Description

UASt regulatory sequences drive expression of the Tdc2 coding region.

(Cole et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Tdc2
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      Scer\GAL4alrm.PD, Tdc2UAS.cCb has lethal phenotype, suppressible by Ctet\tetXTNT-LC.UAS, Scer\GAL4alrm.PD

      (Lee et al., 2021)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Tdc2UAS.cCb/Scer\GAL4Tdc2.PC partially rescues Tdc2RO54

      (Cole et al., 2005)
      Fails to rescue

      Tdc2UAS.cCb/Scer\GAL4Tdc2.PC fails to rescue Tdc2RO54

      (Hardie et al., 2007)
      Comments

      Expression of Tdc2Scer\UAS.cCb, under the control of Scer\GAL4Tdc2.PC, partially rescues the egg retention phenotype of Tdc2RO54 mutants. This expression also increases levels of tyramine and octopamine in the brains of Tdc2RO54 flies.

      (Cole et al., 2005)
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Tdc2Scer\UAS.cCb
      Tdc2UAS.cCb
      Name Synonyms
      Saccharomyces cerevisiae UAS construct b of Cole
      (Cole et al., 2005)
      Secondary FlyBase IDs
        References (4)