FB2024_03 , released June 25, 2024
Allele: Dmel\trpMB03672
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General Information
Symbol
Dmel\trpMB03672
Species
D. melanogaster
Name
FlyBase ID
FBal0192468
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
trpMB
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Mutant adults show only a transient electroretinogram response to light, in contrast to the sustained response seen in wild-type flies.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    NOT Enhanced by
    NOT suppressed by
    Statement
    Reference
    Suppressor of
    Statement
    Reference
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    Additional homozygosity for trpMB03672 rescues the circadian rhythmicity defects observed in cry01, norpA36 double homozygous adults previously trained under 12h:12h light:dark cycles.

    The electroretinogram defects seen in trpMB03672 flies are not altered if the flies are also mutant for one of Xport-A1, Xport-BΔB or Df(3R)Xport-ΔAB.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (1)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    References (7)