FB2024_03 , released June 25, 2024
Allele: Dmel\Dronc+t.drf
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General Information
Symbol
Dmel\Dronc+t.drf
Species
D. melanogaster
Name
FlyBase ID
FBal0193077
Feature type
allele
Associated gene
Dmel\Dronc
Associated Insertion(s)
Carried in Construct
P{drf}
Key Links
Transgenic product class
genomic_DNA
(Daish et al., 2004)
wild_type
(Daish et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Daish et al., 2004)
wild_type
(Daish et al., 2004)
Mutagen
in vitro construct
(Chew et al., 2004)
Progenitor genotype
Carried in construct
P{drf}
Cytology
Description

3.578kb genomic fragment covering the Nc and CG6685 genes. A frameshift mutation has been introduced into the CG6685 gene.

(Daish et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
Dronc
Encoded product / tool
Dronc
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Dronc+t.drf partially rescues Dronc51

      (Chew et al., 2004)
      Comments

      Nc+t.drf rescues the partially lethality of Nc51/Nc51 homozygotes with a few animals rescued to adulthood and up to 50% reaching the pharate adult stage. The delays in larval moults seen in Nc51/Nc51 animals are also partially rescued by this transgene.

      (Chew et al., 2004)

      "CG6685[4]" animals (Df(3L)NcZ homozygotes in which Nc function, but not CG6685 function, is rescued by homozygosity for P{drf}) show late larval lethality with melanotic tumours.

      32.67% of the expected number of Df(3L)NcZ homozygotes which carry both P{drf} and P{CG6685+tDa} survive to eclosion. The remaining noneclosed animals develop to an advanced pharate adult stage.

      (Daish et al., 2004)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Dronc+t.drf
      Nc+t.drf
      Name Synonyms
      Secondary FlyBase IDs
        References (3)