FB2024_03 , released June 25, 2024
Allele: Dmel\talNoB.UAS
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General Information
Symbol
Dmel\talNoB.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0198107
Feature type
allele
Associated gene
tal
Associated Insertion(s)
Carried in Construct
P{UAS-tal.NoB}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Galindo et al., 2007)
Progenitor genotype
Carried in construct
P{UAS-tal.NoB}
Cytology
Description

UASt regulatory sequences drive expression of tal coding sequences in which there is a mutation of the putative start codon of the one type-B ORF, thus preventing its translation.

(Galindo et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
tal
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of talNoB.Scer\UAS in the dorsal leg, under the control of Scer\GAL4dpp.blk1, produces transformation of the distal tibia and fusion to tarsus 1, and ectopic sex combs in tarsi 1 and 2. These phenotypes are compatible with a transformation of tibial identity towards tarsus.

      Ectopic expression of talNoB.Scer\UAS in the embryonic head, under the control of Scer\GAL4Dll-md23 produces extra sclerotised elements in the cephalopharyngeal skeleton.

      Expression of priNoB.Scer\UAS in the dorsal leg, under the control of Scer\GAL4dpp.blk1, produces transformation of the distal tibia and fusion to tarsus 1, and ectopic sex combs in tarsi 1 and 2. These phenotypes are compatible with a transformation of tibial identity towards tarsus.

      Ectopic expression of priNoB.Scer\UAS in the embryonic head, under the control of Scer\GAL4Dll-md23 produces extra sclerotised elements in the cephalopharyngeal skeleton.

      (Galindo et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4unspecified/talNoB.UAS rescues talunspecified

      (Galindo et al., 2007)
      Comments

      Expression of priNoB.Scer\UAS under the control of Scer\GAL4unspecified rescues the priunspecified phenotypes in the adult and the embryo.

      (Galindo et al., 2007)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      priNoB.Scer\UAS
      talNoB.Scer\UAS
      talNoB.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)